Nova Publishers
My Account Nova Publishers Shopping Cart
HomeBooksSeriesJournalsReference CollectionseBooksInformationSalesImprintsFor Authors
  Top » Catalog » Books » Biology » Biology - General » Advances in Medicine and Biology. Volume 9 Chapters » My Account  |  Cart Contents  |  Checkout   
Quick Find
Use keywords to find the product you are looking for.
Advanced Search
What's New? more
_Cancer Research Journal - This journal ceased publication after 4#4 (2010). Back Issues are available.
Shopping Cart more
0 items
Shipping & Returns
Privacy Notice
Conditions of Use
Contact Us
Notifications more
NotificationsNotify me of updates to Reprogrammed Glucose Metabolic Pathways of Inhibitor-Tolerant Yeast, pp. 159-186
Tell A Friend
Tell someone you know about this product.
Reprogrammed Glucose Metabolic Pathways of Inhibitor-Tolerant Yeast, pp. 159-186 $0.00
Authors:  (Z. Lewis Liu, Menggen Ma, Michael A. Cotta, Bioenergy Research, National Center for Agricultural Utilization Research, U.S. Department of Agriculture, Agricultural Research Service, Peoria, Illinois)
Representative inhibitory compounds such as furfural and 5-hydroxymethylfurfural generated from lignocellulosic biomass pretreatment inhibit yeast growth and interfere with the subsequent ethanol fermentation. Evolutionary engineering under laboratory settings is a powerful tool that can be used to generate valuable strains and knowledge for inverse metabolic engineering for strain improvement. An inhibitor-tolerant ethanologenic yeast Saccharomyces cerevisiae developed via evolutionary engineering underwent a genomic adaptation with global integrations for acquired tolerant functions while producing ethanol. Gene expression data provide informative phenotypes and significant insight into molecular mechanisms of the tolerance in yeast. Unification of gene expression data analysis is urgently needed to efficiently utilize the massive amount of data resource from individual research efforts as well as for the expression community in general. A rigorously tested and validated pathway-based real time qRT-PCR array assay applying robust mRNA reference and a master equation provide reliable means for reproducible and comparable expression data analysis. Advances in enhanced expression technology has led to discoveries of new gene functions and interactions to form hypothesis and construct reprogrammed pathways for the tolerant yeast in response to the inhibitor stress. Enriched genetic makeup, continued enhanced expression of genes in maintaining energy and redox balance, and the reprogrammed glucose metabolic pathways globally enable the yeast tolerance. Findings of recent research aid understanding of molecular mechanisms of stress tolerance and guide metabolic engineering efforts for future robust strain development to support biofuels industry. 

Available Options:

  Open Access item.
  Click below PDF icon for free download.


This is an Open Access item. Click above PDF icon for free download.
Special Focus Titles
01.Violent Communication and Bullying in Early Childhood Education
02.Cultural Considerations in Intervention with Women and Children Exposed to Intimate Partner Violence
03.Chronic Disease and Disability: The Pediatric Lung
04.Fruit and Vegetable Consumption and Health: New Research
05.Fire and the Sword: Understanding the Impact and Challenge of Organized Islamism. Volume 2

Nova Science Publishers
© Copyright 2004 - 2020

Reprogrammed Glucose Metabolic Pathways of Inhibitor-Tolerant Yeast, pp. 159-186