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Recent Advancement of Ceramics in Biomedical Research pp. 1-85 $100.00
Authors:  (Samit Kumar Nandi, Biswanath Kundu, Debabrata Basu, Rupnarayan Bhattacharya, Department of Veterinary Surgery and Radiology, West Bengal University of Animal and Fishery Sciences, Kolkata, India, and others)
Abstract:
Over the past 30 years, within an enormous array of biomaterials proposed as ideal scaffolds for cell growth owing a few have demonstrated clinical efficacy. With the advances in modern health care, the quality and life expectancy of human population have significantly improved and accordingly, the need for advanced biomaterials to treat bone defects and repairs along with enhanced fracture healing and distraction osteogenesis is growing, both for preventive as well as curative purposes. Biomaterials, regardless of their categories or classes need to be biocompatible, ideally osteoinductive, osteoconductive, integrative, porous and mechanically compatible with native bone to fulfill desired role in bone tissue engineering. Bioactive classes of ceramics are crucial for development of medical devices bone grafts; as injectable and easily moldable formable ingredients for void fillers (calcium phosphate cement). Further the material finds its application as coatings to improve the biocompatibility of metal implants, resorbable lattices as temporary structures, as drug delivery system, material for spinal surgery and also as orbital implants. Recently, research has been initiated to study the effect of electrical polarization on surface modification of hydroxyapatite to stimulate growth of new bone at a faster rate for quick healing after spinal fusion surgery. Moreover, ceramic nano-particulate systems have been found to be useful for delivery of growth factors and anticancerous drugs due to enhanced bioavailability, predictable therapeutic response and prolonged drug release time. Research programme has also been directed to develop stem cell impregnated bioceramics to obtain ideal bone graft substitutes for animal and human application. 


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Recent Advancement of Ceramics in Biomedical Research pp. 1-85