Nosocomial Fungal Infection in Immunocompromised Patients: Neonates, Diabetic, Cancer and Renal Failure Patients pp. 329-342
Authors: (Amany El Sharif, Department of Microbiology and Immunology, Faculty of Pharmacy, Al-Azhar University, Cairo, Egypt)
Abstract: The list of immunocompromised patients is escalating and includes large and heterogeneous groups of patients. Fungal infections arise when either the fungal exposure is in exceptional high concentration, or where the subject is compromised, that is when natural immunity is decreased by other diseases or during treatment with drugs such as immunosuppressants, chemotherapeutics, or antibiotics. Opportunistic mycoses are fungal diseases of man and animals, caused by fungi which are generally saprobes. These mycoses have increased progressively as a result of the favorable factors for opportunistic fungal infections which have evolved. An increasing range of fungi involved in such diseases is being of world wide distribution. Nosocomial infection is the main source of fungal infection among immunocompromised patients; the list includes patients with diabetes mellitus, cancer patients, neonates and patients with renal failure. Those groups will be briefly discussed in this chapter.