Campylobacter spp. Responses to the Environment and Adaptations to Hosts (pp. 217-253)
Authors: (Tania E. Farrar, Arinze S. Okoli, and George L. Mendz, School of Medicine, Sydney, The University of Notre Dame, Darlinghurst, Australia)
Abstract: Campylobacteriosis is the most common foodborne bacterial infection in the world. Most of the 17 species of bacteria of the genus Campylobacter have been found in human hosts, but 95% of infections are caused by the species C. jejuni and C. coli which are transmitted principally through water and food. Understanding the mechanisms employed by these pathogens that enable them to survive in the environment and in various animal hosts will help to design strategies to limit food contamination and agents that combat the diseases caused by them. Some Campylobacter responses and adaptations to their milieux are unique to these bacteria and represent novel potential targets for therapeutic intervention.