Quorum Sensing Regulation of Pathogenesis and Environmental Survival in Foodborne Vibrios (pp. 595-616)
Authors: (Amy M. Tsou, and Jun Zhu, University of Pennsylvania School of Medicine, Philadelphia, USA)
Abstract: Single-celled bacteria are able to produce and respond to small diffusible molecules called autoinducers. These molecules accumulate as cell density increases and regulate the expression of a range of genes to control a variety of physiological functions in a process known as quorum sensing. Vibrios are commonly found in aquatic environments as free-living organisms or in biofilms. Vibrios also interact with various hosts. Many Vibrio species have been shown to harbor quorum sensing networks that are used to regulate phenotypes important for environmental survival and virulence in response to changes in cell density. In this chapter, we will introduce quorum sensing regulatory pathways in V. fischeri, V. harveyi, V. cholerae, V. vulnificus, and V. parahaemolyticus.