Nova Publishers
My Account Nova Publishers Shopping Cart
HomeBooksSeriesJournalsReference CollectionseBooksInformationSalesImprintsFor Authors
            
  Top » Catalog » Books » Biology » Biology - General » Advances in Medicine and Biology. Volume 50 Chapters » My Account  |  Cart Contents  |  Checkout   
Quick Find
  
Use keywords to find the product you are looking for.
Advanced Search
What's New? more
Doxycycline: Medical Uses and Effects
$73.80
Shopping Cart more
0 items
Information
Shipping & Returns
Privacy Notice
Conditions of Use
Contact Us
Notifications more
NotificationsNotify me of updates to Study on Urinary Iodine and Thiocyanate Concentrations in Bulgarian Schoolchildren and Students (pp. 183-194)
Tell A Friend
 
Tell someone you know about this product.
Study on Urinary Iodine and Thiocyanate Concentrations in Bulgarian Schoolchildren and Students (pp. 183-194) $100.00
Authors:  (Aneliya V. Bivolarska, Penka D. Gatseva, Mariana D. Argirova, Dept. of Chemistry and Biochemistry, and Dept. of Hygiene, Ecology and Epidemiology, Medical University of Plovdiv, Bulgaria)
Abstract:
The role of iodine deficiency as an environmental determinant in the development of endemic goiter is firmly established. However, iodine deficiency does not always result in endemic goiter, and iodine supplementation does not completely prevent goiter. Even in the presence of extreme iodine deficiency there is an unequal geographic distribution of goiter. It is clear, therefore, that there are other factors, beyond iodine deficiency, that may play a role in the etiopathogenesis of endemic goiter. Most of the substances considered to be goitrogens are chemicals found in the environment, e.g. thiocyanates, competitively inhibit the iodine uptake and its organification in the gland.
The aim of this study was to evaluate the association between urinary iodine as reliable indicator of recent iodine status and urinary thiocyanate concentration supposedly related to tobacco smoke exposure of schoolchildren and university students. Subjects of study were 123 children (66 boys and 57 girls) aged 8 to 11 years and 104 medical students (51 men and 53 women) aged 19 to 25 years, all of them from the town of Plovdiv, Bulgaria. Urinary iodine was measured by the Sandell-Kolthoff reaction. The method for thiocyanate determination in urine was based on the quantitative oxidation of thiocyanate in acid permanganate solution with liberation of HCN, which reacted with picric acid. A questionnaire filled by the schoolchildren and students was used to evaluate their exposure to tobacco smoke and their smoking habits.
The median urinary iodine of the inspected schoolchildren was between 100-199 μg/L, which is an indicator of optimal iodine nutrition. However, 10.6% of the children had iodine deficiency. Statistically significant association between tobacco smoke exposure and the values of urine thiocyanate concentration in the inspected children was found. The median urinary iodine of the inspected students was 141 μg/L for the men and 130 μg/L for the women, which indicates optimal iodine nutrition. Around one-third of the subjects were with iodine deficiency though mild iodine deficiency was dominated. There were statistically significant differences between urinary thiocyanate concentrations in smokers and non-smokers (P < 0.0001) with higher thiocyanate values in smokers. None of the studied subjects has a ratio urinary iodine/thiocyanate (g/mg) below 3.5. The quantification of thiocyanate ions in urine provides a fast non-invasive method to monitor thiocyanate load from tobacco smoke. Thiocyanate levels should be carefully controlled in cases of severe iodine deficiency to avoid the competitive inhibition of iodine intake. 


Available Options:
Version:
Special Focus Titles
01.Violent Communication and Bullying in Early Childhood Education
02.Cultural Considerations in Intervention with Women and Children Exposed to Intimate Partner Violence
03.Chronic Disease and Disability: The Pediatric Lung
04.Fruit and Vegetable Consumption and Health: New Research
05.Fire and the Sword: Understanding the Impact and Challenge of Organized Islamism. Volume 2

Nova Science Publishers
© Copyright 2004 - 2020

Study on Urinary Iodine and Thiocyanate Concentrations in Bulgarian Schoolchildren and Students (pp. 183-194)