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01.Pharmacological Activity-Based Quality Control of Chinese Herbs
02.Anticancer Drugs: Design, Delivery and Pharmacology
03.Research Progress on Epinephrine
04.Coumarin Anticoagulant Research Progress
05.Amphetamines: Neurobiological Mechanisms, Pharmacology and Effects
06.Biopharmaceutics and Drug Hypersensitivity
07.Cox-2 Inhibitor Research
08.Curcumin: Biosynthesis, Medicinal Uses and Health Benefits
09.Degradation of Poly (Lactide)- Based Biodegradable Materials
10.Drugs: Approval and Evaluation, Delivery and Control
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Cox-2 Inhibitor Research
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Editors: Maynard J. Howardell
Book Description:
COX-2 Inhibitors are newly developed drugs for inflammation that selectively block the COX-2 enzyme. Blocking this enzyme impedes the production of the chemical messengers (prostaglandins) that cause the pain and swelling of arthritis inflammation. Cox-2 inhibitors are a new class of nonsteroidal anti-inflammatory drugs (NSAIDS). Because they selectively block the Cox-2 enzyme and not the Cox-1 enzyme, these drugs are uniquely different from traditional NSAIDS. This new book explores new research in this field.

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Table of Contents:

Chapter 1. Cyclooxygenase-2 Inhibitor and Gastric Cancer, pp. 1-83
(Yumin Li, Raaj K Praseedom, and Andrew Butler et al., University of Cambridge, UK).

Chapter 2. Prevention and Chemoprevention of Gastric Cancer: Dietary Habits, Helicobacter pylori and COX-2 Inhibitors, pp. 85-114
(Gerardo Nardone and Alba Rocco, University ”Federico II, Italy).

Chapter 3. Cyclooxygenases in Cancer, pp. 115-143
(Daniela Fodera, and Nadia Lampiasi, Instituto di Biomedicina e Immunologia Molecolare “Alberto Monroy”, Italy and Antonella Cusimano et al., Universita di Palermo, Italy).

Chapter 4. Nephrotoxicity of Nonsteroidal Anti-Inflammatory Drugs: Focus on Selective Cyclooxygenase-2 (COX-2) Inhibitors, pp. 145-180
(Steven G. Coca and Mark A. Perazella, Yale University School of Medicine, CT).

Chapter 5. Are COX-2 Inhibitors Active on Intracellular Oxidative Processes? A Study on In Vitro and Cellular Models, pp. 181-207
(Ange Mouithys-Mickalad, Ginette Deby-Dupont, and Carol Deby et al., Institute of Chemistry, Belgium).

Chapter 6. Theoretical Mechanism Studies on Dual Inhibition of Human Cyclooxygenase-2 and 5-Lipoxygenase by Diaryl-Pyrrolizine Derivatives, pp. 209-235
(R. Pouplana, C. Perez, and J. Ruiz, Universitat de Barcelona, Spain).


   Binding: Hardcover
   Pub. Date: 2006
   ISBN: 978-1-59454-994-6
   Status: AV
Status Code Description
AN Announcing
FM Formatting
PP Page Proofs
FP Final Production
EP Editorial Production
PR At Prepress
AP At Press
AV Available
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02.Cultural Considerations in Intervention with Women and Children Exposed to Intimate Partner Violence
03.Chronic Disease and Disability: The Pediatric Lung
04.Fruit and Vegetable Consumption and Health: New Research
05.Fire and the Sword: Understanding the Impact and Challenge of Organized Islamism. Volume 2

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Cox-2 Inhibitor Research