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Electro-Magnetic Field Induced Entropy Production in a Cell: Its Difference between Cancerous and Normal Cells (pp. 309-330) $0.00
Authors:  (Liaofu Luo, Changjiang Ding, School of Physical Science, Inner Mongolia University, Hohhot, China, and others)
Abstract:
Entropy production is a thermodynamic quantity of fundamental importance for a living system. The general relations between entropy production,entropy flow and information flow are discussed. The entropy production rate in a cell under electro-magnetic field is calculated. The special efforts are focused on the comparison of two kinds of cells, healthy cell and cancerous cell. It is demonstrated that the ratio of the field-induced entropy production between cancerous and normal cells depends on a function of dielectric permittivity and specific electro-conductivity of two kinds of cells. In a wide range of dielectric parameter choice the field-induced entropy production for a healthy cell is higher than that for cancerous. Then, based on the comparative measurement of entropy production rates in a pair of normal cell (human breast epithelial cell MCF10A or hepatoma cell line HL-7702) and cancerous cell (human breast cancer cell MDA-MB-231 or hepatic cell line SMMC-7721) under alternating electric field we proved that for both two cell lines the field-induced entropy production for normal cells is obviously higher than cancerous in a large range of field strength from 5 to 25V/cm which gives direct experimental support to above theoretical estimates. It means that the applied field may reverse the direction of entropy-information flow between two kinds of cells and therefore have some therapeutic effect for organisms. 


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Electro-Magnetic Field Induced Entropy Production in a Cell: Its Difference between Cancerous and Normal Cells (pp. 309-330)