Book Description:
The book discusses in detail new aspects of the metabolic basis of important chronic liver diseases. Entities such as non-alcoholic fatty liver disease (fatty liver and Non-Alcoholic SteatoHepatitis - NASH), diabeties in chronic hepetitis C, hemochromatosis, Wilson's disease, Gaucher disease, porphyria, as well as liver cirrhosis and its metabolic consequences will be discussed in detail. These clinical conditions are highly prevalent and affect millions of patients in the USA and worldwide. For example, non-alcoholic fatty liver disease is the most common cause of elevated liver enzymes in the general population. This field has been practically transformed over the last few years, with many new insights gained, regarding both pathogenesis and effective novel treatments.

Table of Contents:
Preface

Biographical Sketches of Editors and Contributors

Chapter I - Pathophysiology of NASH; pp. 1-70
(Metin Basaranoglu and Brent A.Neuschwander-Tetri, Selcuk University Medical School, Turkey and Saint Louis University, USA)

Chapter II - Nonalcoholic Fatty Liver Disease and NASH: Clinical and Histological Aspects; pp. 71-109
(Phunchai Charatcharoenwitthaya & Keith D. Lindor, Mayo Clinic and Foundation, USA)

Chapter III - The treatment of Non-alcoholic fatty liver disease- an entity in evolution; pp. 111-133
(Stephen DH Malnick, Yitzhak Halperin and Lee M Kaplan,
Kaplan Medical Center, Israel, Barzilai Medical Center, Israel
and Massachusetts General Hospital and Harvard Medical School, USA)

Chapter IV - The Hepatitis C Virus and Diabetes Mellitus Association:
Characterization and Studies of Risk Factors, Mechanisms, Implications and Treatment; pp. 135-155
(Hilla Knobler and Ami Schattner, Hebrew University Hadassah Medical School, Israel)

Chapter V - Hereditary Hemochromatosis; pp. 157-174
(Elena Corradini, Francesca Ferrara and Antonello Pietrangelo,
University of Modena and Reggio Emilia
Policlinico, Italy)

Chapter VI - Iron in Chronic Liver Disease; pp. 175-199
(John K. Olynyk, John Ombiga, Debbie Trinder and Bruce R. Bacon, University of Western Australia, Fremantle Hospital, Western Australia, The Western Australian Institute of Medical Research and the Western Australia and Saint Louis University, USA)

Chapter VII - Wilson's Disease; pp. 201-223
(Peter Ferenci)

Chapter VIII - Gaucher Disease; pp. 225-243
(Ari Zimran, Deborah Elstein and Stephan vom Dahl
(Shaare Zedek Medical Centre, Israel and St. Franziskus-Hospital, Cologne, Germany)

Chapter IX - The clinical features and pathobiology of á1-antitrypsin deficiency; pp. 245-267
(Russell L Phillips, Meera Mallya and David A Lomas, Cambridge Institute for Medical Research, UK)

Chapter X - Glycogen Storage Diseases; pp. 269-295
(Joseph I. Wolfsdorf and David A. Weinstein, Harvard Medical, Boston, USA, Children’s Hospital Boston and University of Florida College of Medicine, USA)

Chapter XI - Liver Transplantation for Metabolic Disease; pp. 297-336
(Narendra Siddaiah, University of Washington Medical Center, USA and Kris V. Kowdley)

Index