Functional anatomy of the mitral valve: surgical perspective of mitral valve disease. Setting the field for percutaneous valve repair (pp. 391-408)
Authors: (Joanna Chikwe and David Adams)
Abstract: Mitral valve repair is the only treatment known to restore normal life expectancy to patients with severe mitral regurgitation, but despite repair rates of 90% at high volume centres [2-5], overall repair rates in Europe and the US average less than 50%[6-8]. The wide variation in successful repair primarily reflects the extremely heterogeneous morphology of regurgitant valves, which poses a particular challenge to percutaneous repair techniques. This chapter focuses on the functional anatomy and pathology of the mitral valve from a surgical perspective, providing an insight into the impact of valve morphology on the potential applications and limitations of percutaneous approaches to mitral regurgitation.