Nutritional status of Nigerian children with sickle cell anaemia in stable state (pp. 229-235)
Authors: Barakat A Animasahun, Urowoli P Nwodo, Adaobi N Izuora, and Olisamedua F Njokanma
Abstract: Sickle cell anaemia has multi-systemic manifestations and is associated with severe morbidity and high mortality. It commonly affects growth leading to wasting and stunting. The study aimed to determine the nutritional status using anthropometry, of children with homozygous sickle cell anaemia (SCA), aged one year to ten years in steady state at the Lagos University Teaching Hospital (LUTH). Methods: A cross-sectional study involving 100 children with sickle cell anaemia and 100 age, sex, and social class matched controls that fulfilled the inclusion criteria. Height and weight were measured while Weight-for- age, Height- for- age and Weight-for-height and their z scores were derived from NCHS standard while Body mass index was calculated using the formula Weight in kg/ Height in m2 in Kg/m2 . Results: The study demonstrated a significantly lower mean weight and weight-for-height in the SCA patients than those of controls (p < 0.001) irrespective of gender, however, female SCA patients were shorter than their healthy controls. There was no significant difference with respect to BMI. The z score analysis revealed that SCA patients had significantly lower z scores for height-for-age, and weight-for-age compared with controls (p< 0.02). Further analysis by sex revealed that the difference was more marked in males than in the females. Conclusion: The study revealed age related poor nutritional status in children with sickle cell anaemia compared with contemporary healthy controls and there was no association between anthropometry of subjects and haemoglobin concentration.