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Creutzfeldt-Jakob Disease: New Research
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Editors: Mic J. Stones
Book Description:
Creutzfeldt-Jakob Disease is a very rare and incurable degenerative neurological disorder that is ultimately fatal. It is the most common of the transmissible spongiform encephalopathies. Transmissible spongiform encephalopathy diseases (also known as prion diseases) are caused by a unique type of infectious agent called prions, an abnormally structured form of a protein found in the brain. Other prion diseases include Gerstmann-Sträussler-Scheinker syndrome (GSS), fatal familial insomnia (FFI) and kuru in humans, as well as bovine spongiform encephalopathy (BSE) and scrapie in animals. This book presents the latest research in this field.

Table of Contents:
Preface (pp. vii-xi)

Chapter I - Creutzfeldt-Jakob Disease: Evidence for Autoimmunity Triggered by Microbial Infection; (pp. 1-2)
(Alan Ebringer and Taha Rashid, King's College London, UK)

Chapter II - Psychiatric Features of Sporadic and new Variant Creutzfeldt-Jakob Disease; (pp. 21-36)
(Alain Dervaux and Hubert Lainé, Centre Hospitaler Sainte-Anne, France)

Chapter III - Familial CJD - What Triggers the Disease Onset?;
(pp. 37-52)
(Ariela Gigi, College of Judea and Samaria, Israel and Reuven Babai, Tel Aviv Univ., Israel)

Chapter IV - Pathological Changes in the Primary Visual Cortex (Area V1) in Creutzfeldt-Jakob Syndrome; (pp. 53-70)
(Richard A. Armstrong, Aston Univ., UK)

Chapter V - Neuronal Cyclooxygenase-2, MCL-1, BCL-Xs, BAX, caspase-6 and -8 Accumulation in Brains of Patients with Creutzfeldt-Jakob Disease: Friend or Foe?; (pp. 71-85)
(Martin H. Deininger, Univ. of Freiburg Medical School, Germany and Richard Meyermann, Univ. of Tuebingen Medical School, Germany)

Chapter VI - Coexistence of Alzheimer's Disease with Creutzfeldt-Jakob Disease; (pp. 87-108)
(Osamu Yokota and Kuniaki Tsuchiya, Tokyo Institute of Psychiatry, Japan)

Chapter VII - Modelling the Growth of Prion Aggregates in the Brain in Variant Creutzfeldt-Jakob Disease; (pp. 109-126)
(Richard A. Armstrong, Aston Univ., UK)

Chapter VIII - vCJD and the Unbounded Legacy of BSE; (pp. 127-146) (Eric P.M. Grist, Univ. of South Bohemia, Czech Republic)

Index (pp. 147-159)

   Binding: Hardcover
   Pub. Date: 2007
   ISBN: 1-60021-345-6
   Status: AV
Status Code Description
AN Announcing
FM Formatting
PP Page Proofs
FP Final Production
EP Editorial Production
PR At Prepress
AP At Press
AV Available
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