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01.Renin-Angiotensin System: Physiology, Role in Disease and Health Implications
02.Melatonin: From Molecules to Therapy
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05.Melatonin: From Molecules to Therapy (For Contributors Only - Special Price of $75 to Expire on March 4, 2008)
06.Liver Cirrhosis: New Research
07.New Research on Signal Transduction
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09.Prostate Cancer (Horizons in Cancer Research, Volume 1)
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New Research on Signal Transduction
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Editors: Bruce R. Yanson
Book Description:
In many transduction processes, an increasing number of enzymes and other molecules become engaged in the events that proceed from the initial stimulus. In such cases the chain of steps is referred to as a "signaling cascade" or a "second messenger pathway" and often results in a small stimulus eliciting a large response. Hormones and other signaling molecules may exit the sending cell by exocytosis or other means of membrane transport. The sending cell is typically of a specialized type. Its recipients may be of one type or several, as in the case of insulin, which triggers diverse and systemic effects. This book sheds new light in this exciting field of cell transportation research.

Table of Contents:

Chapter 1.-BUB, Mad and the Mitotic Spindle Checkpoint Control: New Trends in Check Point Signalling; pp. 1-36
(Victor Martin Bolanos-Garcia, Univ. of Cambridge, UK)

Chapter 2.-Prion Proteins in Signal Transduction; pp. 37-61
(Neville Vassallo, Univ. of Malta, Malta and Jochen Herms, Ludwig Maximilians Univ., Germany)

Chapter 3.-Protein Kinases C: Evergreen Players in Old and New Signal Transduction Cascades; pp. 63-77
(Alessia Pascale, Marialaura Amadio, Department of Experimental and Applied Pharmacology, Italy and Fiorenzo Battaini, Univ. of Roma, Italy)

Chapter 4.-Reciprocal Synergism at Early Stages of Transduction Pathways Allows Efficient Cell Signalling; pp. 79-92
(Nelson P. Barrera, Univ. of Cambridge, UK, Bernardo Morales, Univ. de Santiago, Chile and Manuel Villalon, Pontificia Univ. Cat¨®lica de Chile, Chile)

Chapter 5.-General Aspects of Sphingolipid Signalling; pp. 93-113 (In¨¦s D¨ªaz-Laviada, Univ. of Alcal¨¢, Spain)

Chapter 6.-"Omic" Approaches to Signal Transduction; pp. 115-139 (Guanghui Hu and Mark Hurle, GlaxoSmithKline, USA)

Chapter 7.-De Novo Signalling Pathway Reconstruction from Multiple Data Sources; pp. 141-163
(Dongxiao Zhu, Stowers Institute for Medical Research, USA, Michael G. Rabbat, Univ. of Wisconsin, USA and Alfred O. Hero, III et al., Univ. of Michigan, USA)

Chapter 8.-Protein Tyrosine Phosphatase PTP1B in Signal Transduction of Hematopoietic Stem/progenitor Cells; pp. 165-187
(Gang-Ming Zou, Indiana Univ. School of Medicine, USA)

Chapter 9.-The Increased Expression of SnoN and Undetectable Levels of Important Cell Cycle Regulators, Proteins p21Waf1/Cip1 and p27Kip1 as Probable Causes of the Resistance of ML-2 Cells Proliferation to Transforming Growth Factor-¦Â1; pp. 189-209
(Dana Provaznikova, Gabriela Peslova and Iuri Marinov et al., Institute of Hematology and Blood Transfusion, Czech Republic)

Chapter 10.-Angiotensin II Signalling in Cardiomyocytes;
pp. 211-229
(Sibylle Wenzel and Klaus-Dieter Schl¨¹ter, Justus -Liebig Univ., Germany)

Chapter 11.-Postconditioning the Heart; pp. 231-250
(Pasquale Pagliaro and Claudia Penna, Biologiche Univ. de Torino, Italy)


   Binding: Hardcover
   Pub. Date: 2007
   ISBN: 1-60021-379-0
   Status: AV
Status Code Description
AN Announcing
FM Formatting
PP Page Proofs
FP Final Production
EP Editorial Production
PR At Prepress
AP At Press
AV Available
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