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Cell Apoptosis and Cancer
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Editors: Albina W. Taylor
Book Description:
Apoptosis is the regulated form of cell death. It is a complex process defined by a set of characteristic morphological and biochemical features that involves the active participation of affected cells in a self-destruction cascade. This programmed cell death plays a critical role in physiological functions such as cell deletion during embryonic development, balancing cell number in continuously renewing tissues and immune system development. Additionally, a dysregulation of apoptosis is underlying in numerous pathological situations such as Parkinson, Alzheimer´s disease and cancer. A number of studies have pointed out an association between consumption of fruits and vegetables, and certain beverages such as tea and wine, which are rich in polyphenols, with reduced risk of chronic diseases, including cancer. Apoptosis is also the regulatory mechanism involved in the removal of unnecessary cells during development and in tissue homeostasis in a wide range of organisms from insects to mammals. Cancer and cell apoptosis is the central focus of this significant new book.

Table of Contents:
Chapter Availability

Individual chapters are available for $25 each by sending an email to Nova will provide the chapter for your easy downloading or send it as an email attachment if you prefer.


Expert Commentary:

Commentary.- Antiapoptotic Activity of Heat Shock Proteins is a Challenge for Cancer Treatment; pp. 3-4
(By Alexander E. Kabakov)

Commentary.- Development of Pro-Apoptotic agents for cancer therapy; pp. 5-6
(T.S.Sridhar, Department of Chemistry and Biochemistry, University of Windsor ON, Canada)


Chapter I.-Cancer Stem Cell and Clustering Metastasis Theory; A Hypothesis for Evasion of Apoptosis in Cancer Metastatic Process; pp. 9-21
(Kanya Honoki, Hiromasa Fujii, and Toshifumi Tsujiuchi ( Dept. of Orthopedic Surgery, Nara Med. Univ., Div. of Life Science and Bioinformatics, Fac. of Science and Technologies, Kinki Univ.)

Chapter II.-Apoptosis as a Consequence of Multiple Organelle Damage in Cultured Tumor Cells after Photosensitization with Rose Bengal Acetate; pp. 23-45
(C.Soldani, M.G.Bottiroli, A.Fraschini, A.C.Croce, G.Bottiroli, A.I. Scavassi And C. Pellicciari)

Chapter III.-Biology of Apoptosis as Predetermined Carcinogenesis; pp. 47-60
(Lawrence M. Agius)

Chapter IV.-Modulating Apoptosis Thresholds in Cancer Therapy;
pp. 61-74
(Christoph Herold and Matthias Ocker)

Chapter V.-Apoptosis in the Battle Field of the Tumor Microenvironment; pp. 75-85
( Yuru Meng and Thomas F. Gajewski)

Chapter VI.-Apoptosis of Leukemia Cells Induced by L-Ascorbic Acid and Arsenic Trioxide: The Effect of Oxidative Stress and Glutathione Homeostasis; pp. 87-112
(Seyeon Park)

Chapter VII.-Apoptosis-Inducing Effects of Curcumin in Adult T-Cell Leukemia Cells; pp. 113-133
(Mariko Tomita and Naoki Mori)

Chapter VIII.-Hyperthermia-Induced Apoptosis; pp. 135-153
(E.H.A. Nijhuis, A.A. Poot, J. Feijen)

Chapter X.-Cathepsin-Regulated Cell Death Pathways: Lysosomes as Targets for Cancer Therapy; pp. 155-180
( Nagathihalli S. Nagaraj and Wolfgang Zacharias)


      Cancer Etiology, Diagnosis and Treatments
   Binding: Hardcover
   Pub. Date: 2007
   ISBN: 1-60021-506-8
   Status: AV
Status Code Description
AN Announcing
FM Formatting
PP Page Proofs
FP Final Production
EP Editorial Production
PR At Prepress
AP At Press
AV Available
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Cell Apoptosis and Cancer