Prevalence and incidence of asymptomatic bacteriuria among Nigerian children and adolescents with type 1 diabetes mellitus (pp. 331-335)
Authors: Alphonsus N Onyiriuka and Edirin O Yusuf
Abstract: It is commonly believed that patients with diabetes mellitus are at increased risk of urinary tract infection compared with non-diabetic patients. Methods: Bacteriuria was screened for in 34 patients (17 with type 1 diabetes mellitus and 17 with non-diabetic endocrine disorders) at their regular follow-up visits collected every three months for 12 months and cultured. The subjects were matched for age and sex. Results: Among the 34 patients screened, only two (one (5.9%) out of 17 diabetics and one (5.9%) out of 17 non-diabetics) had asymptomatic bacteriuria and the urine culture of each of them yielded a growth of Escherichia coli sensitive to gentamycin. The duration of diabetes in the girl with asymptomatic bacteriuria (ASB) was 7 years. She had a poor glycaemic control and some psychosocial challenges. Her pubertal maturation was delayed (Tanner Stage II at the age of 15 years and has not attained menarche). She weighed 29 Kg, with BMI of 16.0 kg/m2. In addition, she had vaginal candidiasis for which she was appropriately treated, using ketconazole. The other patient with ASB was a 7-year-old girl with precocious puberty due to congenital adrenal hyperplasia diagnosed at the age of 18 months. The two patients with ASB did not progress to symptomatic bacteriuria after a follow-up period of one year. Conclusion: The prevalence and incidence of asymptomatic bacteriuria in diabetic children and adolescents do not differ from those of their non-diabetic counterparts.