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01.Evaluation of BodyTalk, a novel mind-body medicine, for chronic pain treatment (pp. 279-290)
02.Topical non-steroidal anti-inflammatory drugs in the treatment of osteoarthritis: A short review (pp. 257-260)
03.Pancreatic cancer with rare leptomeningeal disease: A case report and literature review (pp. 323-327)
04.Dexamethasone preventing dural puncture headache (pp. 273-277)
05.The development of a mindfulness-based stress reduction group for adolescents with chronic pain (pp. 301-312)
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Dexamethasone preventing dural puncture headache (pp. 273-277) $45.00
Authors:  Maher Fawzy Mahmoud, Hassan Mohamed Ali, Mohamed Mourad Hashim, and Ahmed Abdel Kader Fahmy
The usual practice of anaesthesia all over the world for caesarean section is spinal anaesthesia, which is associated with post dural puncture headache (PDPH) as a common complication, Intrathecal dexamethasone hypothetically will prevent PDPH due to its anti-inflammatory effect as it suppresses the inflammatory mediators released after the dural puncture. Methods: A double blinded randomized study of 444 females scheduled for elective Caesarean section were included in this study and allocated to three groups, D4 group (n=138) with 4 mg dexamethasone intrathecal, group D8 (n=151) with 4 mg intrathecal and a control group (n=155) injected with placebo. The three groups were monitored for incidence, severity and duration of PDPH. Results: PDPH developed in 24 cases (17.39%) in D4 group, 26 cases (17.2%) in D8 group and 51 cases (32.9%) in control group (p value >0.05), there was no significant difference in the incidence, severity or duration of PDPH between D4 and D8 groups (p>0.05). Ephedrine dose requirement in D4 (15.329.252) and in D8 (14.1115.19), while in the control group it was (27.212.125) with p value<0.01 Conclusions: intrathecal dexamethasone, either 4 mg or 8 mg decrease the PDPH, but with no statistical difference, but as a secondary result it can reduce the hypotension from the spinal anaesthesia (p<0.01). 

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Dexamethasone preventing dural puncture headache (pp. 273-277)