Cutaneous manifestations of endocrine disorders (pp. 67-93)
Authors: Manmohan K Kamboj and Ruqiya Shama Tareen
Abstract: The intricate relationship of cutaneous manifestations of endocrine disorders and their connection with psychosomatic repercussions is quite complex and is being dully recognized. However, more specific interplay of endocrine systems in psychiatric and dermatological disorders is still not very well understood and our knowledge of this area is still in its early phases. The Neuro-Immuno-Cutaneous-Endocrine (NICE) network is one of the emerging models seeking to understand mind-body relationships and their impact on skin. NICE is a construct of four major organ systems and how they are intertwined as well as function with regard to the extensive communication systems of neurochemical signals such as cytokines, neuropeptides, glucocorticoids and other messenger molecules. This discussion seeks to review endocrine disorders and their cutaneous features, along with psychiatric features and principles of clinical management of these cutaneous and psychiatric issues presenting in the context of major endocrine disorders commonly seen in children and adolescents.