Inborn errors of metabolism, psychiatry and dermatology (pp. 95-106)
Authors: Manmohan K Kamboj and Ruqiya Shama Tareen
Abstract: Inborn errors of metabolism (IEMs) may involve any of the physiologic, biochemical, and metabolic pathways characterized by developmental delays, neuropsychiatric manifestations, and characteristic dermatological features. Psychiatric conditions may manifest much earlier and often may be the only type of symptoms presents, predating the presentation of symptoms related to other systems sometimes by many years. The psychiatric and cognitive symptoms seen in IEM are of wide variety and range from vague, nonspecific symptoms to severe psychosis and delirium. Some of these disorders are considered in this discussion with respect to their psychodermatologic aspects.