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Factors and correlates of depression in advanced cancer patients: A scoping review (pp. 67-77) $45.00
Authors:  Michael Puopolo, Eva Bain, Arnav Agarwal, Michael Lam, Edward Chow, and Blair Henry
Abstract:
Depression is common in cancer patients, particularly those in advanced or end stages of the disease. A scoping review was conducted to discover factors and correlates of depression in advanced cancer patients, compare the prevalence of depression in these patients in different care settings, and identify areas that would benefit from further research. Methods: A comprehensive search was conducted using four databases (MEDLINE, Embase, PsychInfo, and Cinahl). Articles were considered eligible if they discussed factors that may lead or correlate to depression in adults with advanced cancer, or if they discussed differences in depression rates between cancer patients in palliative care settings versus other settings. Two reviewers screened identified hits, and extracted data for articles deemed eligible. Results: Nineteen eligible articles were identified. There appeared to be a consensus that having a worse prognosis, poor spiritual health, metastastic disease, cognitive impairment, less control over the course of the illness, fatigue, sleep disorders, a longer illness and being female positively correlated with having depression. There was no such consensus found for differences based on age or care settings. Conclusions: There are a number of factors which contribute to depression in this patient population. Further research should be undertaken to study the major factors identified and guide optimal management in order to improve overall quality of life in advanced cancer patients. 


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Factors and correlates of depression in advanced cancer patients: A scoping review (pp. 67-77)