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Effects of Time-Restricted Meals and Risk of Metabolic Diseases (pp. 59-60) $0.00
Authors:  Narsingh Verma and Smriti Rastogi
Diabetes mellitus is a syndrome of impaired carbohydrate, fat, and protein metabolism caused by either lack of insulin secretion or decreased sensitivity of the tissues to insulin [1]. It is a pandemic with 80% of diabetes patients living in developing countries. The number of diabetics in India is expected to increase to a staggering 109 million cases by 2035 [2]. Daily cyclical changes in light and darkness result in diurnal rhythms in other environmental parameters such as temperature and humidity [3]. A time bound, determinable and strong daily rhythm in food avail-ability and environmental factors has led to the evolution of a 24-hour internal timing mechanism or circadian rhythm that facilitates organisms to have inbuilt knowledge of daily changes and to optimize fitness. Vital to the alternating cycle of feeding and fasting (irrespective of circadian rhythm-proficient or circadian rhythm deficient organisms) is the theory that “fasting physiology” (biochemical processes associated with the process of fasting) is kick started once stored energy is being utilized and therefore, does not occur during the feeding period when more energy is being accumulated [4]. This mini review aims to highlight the role of circadian energy restriction on energy metabolism in patients with diabetes mellitus. 

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Effects of Time-Restricted Meals and Risk of Metabolic Diseases (pp. 59-60)