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The Ten Characteristics of a High Quality Diet with Reference to Circadian Dysfunction? (pp. 207-212) $0.00
Authors:  Ram B. Singh, O. A. Bawareed, Sergey Chibisov, Elena Kharliskaya, Maria Abramova, and Magomedov Magomed
The Western diet (WD) patterns, characterized with high daily intake of saturated and trans fats and refined carbohydrates and poor in vegetables, fruits, nuts and whole grains, often lead to obesity and have been linked to neurodegenerative diseases and circadian dysfunction [1-3]. Moreover, obesity and overweight can also predispose adipocyte hypoxia with increase in pro-inflammatory cytokines, leading to increase in systemic including neuro-inflammation, causing neuronal dysfunction [3]. Apart from these adverse effects of diet, long-term intake of Western type highly palatable foods, may induce oxidative stress and inflammation leading to circadian dys-function due to dysregulation of hypothalamic-pituitary-adrenal (HPA), associated with sleep dis-orders as well as chronic stress, anxiety, and depr-ession [3-6]. Chronic psychological stress can mod-ulate eating behavior and food choices which may have detrimental effects on different brain regions such as the hippocampus, hypothalamus, circadian clock, amygdala, and several cortical brain regions [6]. Western diet may also have adverse effects on gut microbiota leading to brain dysfunction and cardio-metabolic diseases [7, 8]. There is evidence that Mediterranean types of diets such as Indo-Mediterranean diet and Cretan diet have most of the features of high quality diet, which has been demonstrated to cause significant decline in morbidity and mortality [9-11]. These diets are rich in micro-nutrients and nutraceuticals which are responsible for physiological functions including cell signaling. This review of selected studies, summarizes the current scientific evidence about the characteristics of a high quality diet and its protective role against circadian dysfunction. 

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The Ten Characteristics of a High Quality Diet with Reference to Circadian Dysfunction? (pp. 207-212)