Book Description:
Neuroblastoma is a cancer that develops from nerve cells found in several areas of the body. Neuroblastoma most commonly affects children age 5 or younger, though it may rarely occur in older children and adults. Neuroblastoma is the most common cancer in babies. Neuroblastoma develops in tissue that makes up the sympathetic nervous system — the system of nerves that automatically regulates your heart rate, blood pressure and digestion. Neuroblastoma most commonly arises in and around the adrenal glands, which sit atop the kidneys. However, neuroblastoma can also develop in other areas of the abdomen and in the chest, neck and pelvis. This new book presents important new research in this field of research.

Table of Contents:
Preface

Cancer Stem Cell in Neuroblastoma: Diagnostic and Therapeutic Implications
(Hiroaki Komuro, Department of Pediatric Surgery, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Tsukuba, Ibaraki, Japan)pp.1-34

Perspectives of Proteomics Investigations of Neuroblastoma Chemoresistance
(Annamaria D'Alessandro, Valeria Marzano, Simona D' Aguanno, Children's Hospital "Bambino Gesu", IRCCS, Rome, Italy, Dept. of Internal Medicine, Univ. of Rome "Tor Vergata", Rome, Italy, Dept. of Laboratory Medicine, Univ. Hospital of Rome "Tor Vergata", Rome, Italy, et al.)pp.35-56

Down Syndrome's Protection Against Neuroblastoma: The Stromal and Neural Overmaturation Tracks
(Daniel Satgé, Laboratory of Pathology, Centre Hospitalier, Tulle, France, Nicole Créau, Université Paris, Paris, France, Revital Aflalo-Rattenbach, Université Paris, Paris, France, Stéphane Ducassou, Pediatric Oncology, CHU Hautepierre, Strasbourg, France, Patrick Lutz, Pediatric Oncology, CHU Hautepierre, Strasbourg, France, Jean Bénard, Medical Biology and Pathology Department, Institut Gustave Roussy, Villejuif, France)pp.57-100

The P73 Target Genes in Human Malignant Neuroblasts are related to Neuronal Development and Sympathetic Differentiation
(Emilie Horvilleur1, David Goldschneider 1, Jean Bénard 1,2, and Sétha Douc-Rasy 1,3; 1. Centre National de Recherche Scientifique-Unité Mixte de Recherche 8126-Université Paris-Sud 11, Institut Gustave Roussy, Villejuif, France; 2. Département de Pathologie et Biologie Médicales, Institut Gustave Roussy,Villejuif, France; 3. Université Pierre et Marie Curie, Jussieu, Paris, France)pp.101-122

The Relationships are Between the Neuroblastome and Caspases 3, 8, 9
(Jianghua Zhan, General Pediatric Surgery, Associate Professor, Tianjin Medical University, Tianjin Children's Hospital, Liqin Zhang, Department of Gynecologic Cytology, Tianjin General Hospital, Tianjin Medical University, Hong Lin, Department of Pediatric Surgery, Tianjin Children's Hospital)pp.123-128

*Genome and Proteome in Neuroblastoma (Kalliopi Gana et al., University of Athens)pp.129-154

Index pp.155-172