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01.Inflammatory Conditions of the Colon
02.Handbook of Pharyngeal Diseases: Etiology, Diagnosis and Treatment
03.Effects, Diagnosis and Management of Extra-Esophageal Reflux
04.Tumor Budding in Colorectal Cancer: Recent Progress in Colorectal Cancer Research (Horizons in Cancer Research, Volume 8)
05.Crohn's Disease: Etiology, Pathogenesis and Interventions
06.Irritable Bowel Syndrome
07.Focus on Colorectal Cancer Research (Horizons in Cancer Research, Volume 4)
08.Pancreatic Cancer: New Research
09.Sleep Effect on Gastrointestinal Health and Disease: Translational Opportunities for Promoting Health and Optimizing Disease Management
10.Therapeutic Perspectives of Gastrointestinal Melatonin (pp. 233-252)
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Crohn's Disease: Etiology, Pathogenesis and Interventions
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Editors: Jack N. Cadwaller
Book Description:
This new book is devoted to research on Crohn's disease (also known as regional enteritis) which is a chronic, episodic, inflammatory bowel disease (IBD) and is generally classified as an autoimmune disease. Crohn's disease can affect any part of the gastrointestinal tract from mouth to anus; as a result, the symptoms of Crohn's disease vary among afflicted individuals. The disease is characterized by areas of inflammation with areas of normal lining inbetween in a symptom known as skip lesions. The main gastrointestinal symptoms are abdominal pain, diarrhea (which may be bloody, though this may not be visible to the naked eye), constipation, vomiting, weight loss or weight gain. Crohn's disease can also cause complications outside of the gastrointestinal tract such as skin rashes, arthritis, and inflammation of the eye.

Although the cause of Crohn's disease is not known, it is believed to be an autoimmune disease that is genetically linked. The highest relative risk occurs in siblings, affecting males and females equally. Smokers are three times more likely to get Crohn's disease.

Unlike the other major types of IBD, there is no known drug based or surgical cure for Crohn's disease. Treatment options are restricted to controlling symptoms, putting and keeping the disease in remission and preventing relapse.

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Table of Contents:

Short Communication

Enteric Glia Cells and Chronic Inflammatory Bowel Disease pp. 1-8
(Georg von Boyen, Dept. of Medicine I (Gastroenterology), Univ. of Ulm, Max Reinshagen, Dept. of Medicine I, Klinikum Braunschweig)

Laparoscopic-Assisted Ileocecal Resection for Crohn's Disease: Report of Safety and Easy Technique pp. 9-15
(Bedioui H, Chebbi F, Ksantini R, Daghfous A, Surgical Dept. "A", Rabta Hospital, Tunis, Tunisia, et al.)

Research and Review Studies

Surgery for Intestinal Crohn's Disease and Postoperative Management for Prevention of Recurrence: Current Evidence pp. 17-65
(Takayuki Yamamoto, Inflammatory Bowel Disease Center & Dept. of Surgery, Yokkaichi Social Insurance Hospital, Yokkaichi, Mie, Japan)

Dendritic Cells and Intestinal Epithelial Permeability in Crohn's Disease pp. 67-100
(Manuel A. Silva, Dept. of Pathology and Molecular Medicine, Intestinal Disease Research Programme, McMaster Univ., Hamilton, Ontario, Canada, Division of Gastroenterology, Hepatology & Nutrition, Dept. of Pediatrics and of Microbiology and Immunology, Sainte-Justine Research Centre, Univ. of Montreal, Montreal, Canada)

Monitoring Crohn's Disease (CD) pp. 101-120
(Lone G. M. Jorgensen, The Research Unit and Dept. of General Practice, Univ. of Copenhagen, Copenhagen, Denmark)

Surgical Intervention for Small Bowel Crohn's Disease pp. 121-140
(Bobby Dasari, Specialty Registrar,Department of General Surgery, Belfast City Hospital,Belfast, UK)

A Rasch Model of the Crohn's Disease Activity Index (CDAI); Equivalent Levels of Ranked Attribute and Continuous Variable Scales pp. 141-169
(William R. Best)

The Utility of Serological Markers in Inflammatory Bowel Diseases: Gadget or Magic? pp. 171-193
(Maria Papp, Gary L. Norman, Istvan Altorjay, Peter Laszlo Lakatos, Dept. of Gastroenterology, Univ. of Debrecen, Debrecen, Hungary)

Genetics of Crohn's Disease pp. 195-205
(Maria Concetta Renda, Divisione Ematologia II Ospedale V. Cervello, Palermo, Italy, Mario Cottone, Dipartimento di Medicina, Pneumologia e Fisiologia della Nutrizione, Univ. di Palermo, Italy)

Recombinant Human Growth Hormone Treatment in Patients with Growth Deficiency and Crohn's Disease - New Perspectives pp. 207-225
(Mieczyslaw Szalecki, Dept. of Metabolic Diseases, Endocrinology and Diabetology, Children's Memorial Health Hospital, Warszawa, Poland, Jerzy Starzyk, Malgorzata Wojcik, Dept. of Pediatric and Adolescent Endocrinology, Jagiellonian Univ., Collegium Medicum, Krakow, Poland)


   Binding: Hardcover
   Pub. Date: 2008 4th Quarter
   Pages: 7 x 10, 246 pp.
   ISBN: 978-1-60456-993-3
   Status: AV
Status Code Description
AN Announcing
FM Formatting
PP Page Proofs
FP Final Production
EP Editorial Production
PR At Prepress
AP At Press
AV Available
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Crohn's Disease: Etiology, Pathogenesis and Interventions