Book Description:
White matter is the component of the central nervous system charged with propagating the electrical signals of neurons. It is comprised of axons and glial cells, including oligodendrocytes which wrap the axons in lipid rich myelin, giving the tissue the characteristic appearance after which it is named. Understanding the physiology of white matter in health and the pathophysiology that contributes to numerous diseases is a major focus of neuroscience. This book comprises a collection of works on topics pertinent to the study of white matter, ranging from the basic organisation of the tissue to the study of white matter in disease and as a result will be of interest to those working in both basic and clinical science.

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Table of Contents:
Preface

Research and Review Studies

Interhemispheric Connectivity: The Evolution and Nature of the Corpus Callosum pp. 3-15
(Sarah B. Johnson, Manuel F. Casanova - Dept. of Psychiatry, Univ. of Louisville, Louisville, KY)

White Matter Lesions: From Present to Future pp. 17-28
(R.P.W. Rouhl, R.J. van Oostenbrugge, J. Lodder - Dept. of Neurology, Maastricht Univ. Medical Center and others)

White Matter Lesions and Aging in HIV Infection: Implications for Development of Cognitive Decline and Dementia pp. 29-42
(Aaron M. McMurtray, Beau Nakamoto, Kalpana Kallianpur, Erin P. Saito - Dept of Medicine, Neurology, John A. Burns School of Medicine, Univ. of Hawaii, Honolulu and others)

White Matter Changes in Drug Abuse and in HIV-1 Infection^ pp. 43-70
(Andreas Büttner, Jeremias Wohlschlaeger, Ida C. Llenos, Serge Weis, Institute of Forensic Pathology, Ludwig-Maximilians University, Munich, Germany, and others)

White Matter Changes in Critical Illness and Delirium pp. 71-88
(Max L. Gunther, Carlos Faraco, Alessandro Morandi - Vanderbilt Univ. Medical Center, Center for Health Services Research, Nashville, TN and others)

White Matter Involvement in Neuromuscular Disorders pp. 89-109
(Petr Vondracek, Marketa Hermanova, Kristina Vodickova, Lenka Fajkusova, Eva Brichtova Jarmila Skotakova - Dept. of Pediatric Neurology, Univ. Hospital, Brno, Czech Republic and others)

White Matter Hyperintensities in Psychiatric Disorders and their Association with Suicide Risk pp. 111-132
(Maurizio Pompili, Gianluca Serafini, Silvia Rigucci, Andrea Romano, Marco Innamorati, Antonio Del Casale, Alberto Forte, Roberto Tatarelli, David Lester - Dept. of Psychiatry, Sant' Andrea Hospital, Sapienza Univ. of Rome, Italy and others)

A Quantitative Study of the Pathological Changes in the Cortical White Matter in Variant Creutzfeldt-Jakob Disease(vCJD)pp. 133-146
(Richard A. Armstrong - Vision Sciences, Aston Univ., Birmingham, UK)

Progressive Multifocal Leukoencephalopathy pp. 147-164
(Endre Pal - Dept. of Neurology, Univ. of Pecs, Hungary)

Remyelination Failure in Multiple Sclerosis and Vulnerability of Oligodendrocytes to Repeated Insults pp. 165-185
(Catherine Fressinaud - Neurology Dept., Univ. Hospital, Angers, France)

Endoscopic Anatomy of the Thecal Sac Using a Flexible Steerable Endoscope pp. 187-202
(Jan Peter Warnke - Neurosurgical Dept., Paracelsus Clinic, Zwickau, Germany)

White Matter Abnormalities in the Diabetic-Hypertensive Brain ^ pp. 203-227
(Natalia Rincon, Cory Toth, University of Calgary, and others)

Brain Tissue Segmentation Based on Multi-Channel Diffusion Tensor Imaging Data pp. 229-246
(Tianming Liu, Stephen T.C. Wong - Dept of Computer Science, Univ. of Georgia, Athens, GA and others)

Three-Dimensional Microstuctural Analysis of Human Brain Tissue by Using Synchrotron Radiation Microtomographs pp. 247-277
(Ryuta Mizutani, Akihisa Takeuchi, Kentaro Uesugi, Susumu Takekoshi, R. Yoshiyuki Osamura, Yoshio Suzuki - Dept. of Applied Biochemistry, School of Engineering, Tokai Univ., Kitakaname, Japan and others)

Origin and Function of Amoeboid Microglia in the Periventricular White Matter in the Developing Brain pp. 279-298
(C. Kaur, E.A. Ling - Dept. of Anatomy, Yong Loo Lin School of Medicine, National Univ. of Singapore, Singapore)

Diffusion Tensor Imaging Is More Sensitive than Conventional Magnetic Resonance Imaging in Demonstrating White Matter Abnormalities in Susac's Syndrome pp. 299-316
(Ilka Kleffner, Michael Deppe, Siawoosh Mohammadi, Philip Van Damme, Stefan Sunaert, Wolfram Schwindt, Jens Sommer, Peter Young, E.B. Ringelstein - Dept of Neurology, Univ. of Muenster, Muenster, Germany and others)

Organisation of the Node of Ranvier in Myelinated Central Axons pp. 317-333
(James J.P. Alix - Academic Foundation Programme, Dept. of Medicine, Imperial College, London, UK)

Organizing Principles of Projections of the Long Descending Reticulospinal Pathways and their Target's Spinal Commissural Neurons: With Special Reference to the Locomotor Function pp. 335-356
(Kiyoji Matsuyama, Kaoru Yakakusaki - Dept. of Occupational Therapy, Sapporo Medical Univ. School of Health Sciences, Sapporo, Japan and others)

Commentaries

Diffusion Tensor MRI Data Acquisition Methods for White Matter and Clinical Applications: non Echo-planar imaging pp. 359-374
(Department of Radiology, Toho University, 6-11-1 Omori-nishi, Ota, Tokyo, Japan)^

The Dimensions of the Sacral Spinal Canal in Thecaloscopy: A Morphometric MRI Study pp. 375-380
(Sofia Mourgela, A. Sakellaropoulos, S. Anagnostopoulou, J.P. Warnke - Neurosurgical Department,"Agios Savas" Anticancer Institute, Athens, Greece and others)


Index