Book Description:
The number of commercially available antibodies for the detection of biological markers, tumor markers, by immunohistochemistry or serological methods in cancer are rapidly increasing. Results in different studies are often contradictory and the usefulness of single tumor markers in different cancer types is unclear. An increasing number of studies on genetic “fingerprints” are being reported. This book represents the most comprehensive and up-to-date publication on histological and serological tumor markers, also commenting recent genetic studies. Sixteen major cancer types and an additional chapter on HIV-related cancers are reviewed by more than 40 authors. These are cancer of the breast, lung, esophagus, stomach, pancreas, liver, colon, rectum, anus, skin, brain, prostate, penis, ovary, uterus, uterine cervix and HIV-related cancers. The authors are active and respected researchers, experts in their fields. Tumor markers will be evaluated for clinical usefulness in diagnostics, prognosis and therapy. Definitive present usefulness is given for the specific cancer types and their purpose of use. Tumor markers that are still being evaluated but of possible future clinical importance are discussed. The index will make it easy to find a particular tumor marker and compare studies on different cancer types. The book is meant to inspire clinical and laboratory management as well as planning research and evaluation of results. Thus, oncologists, pathologists and other physicians who are involved in patients with cancer will find it useful.

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Table of Contents:
Preface
(Dan Hellberg, Center of Clinical Research, Falun/ Department of Women´s and Children´s Health, Uppsala University, Uppsala, Sweden)

Chapter I. Tumor Markers: Past, Present and Future;pp. 1-15
(Michael J. Duffy, St. Vincent's University Hospital, Dublin, Ireland,and others)

Chapter II. Lung Cancer Tumor Markers;pp. 17-35
(Alissa K. Greenberg and M. Sung Lee,New York University, New York,NY and others)

Chapter III. Histological and Serological Tumor Markers and Their Clinical Usefulness in Skin Cancer;pp. 37-51
(Jochen Utikal, Dirk Schadendorf and Selma Ugurel, Massachusetts General Hospital Cencer Center, Boston, USA, and others)

Chapter IV. Brain Tumors – Prognostic and Predictive Markers;pp. 53-75
(Roger Henriksson, Fredrik Johansson, Mikael Johansson, Thomas Asklund, Erik Blomquist, Stefan Bergström,Simon Ekman and Michael Bergqvist, University Hospital,, Sweden and others)

Chapter V. Molecular Prognostic and Predictive Factors in Esophageal Cancer;pp. 77-92
(Daniel Vallböhmer, Jan Brabender, Ralf Metzger and Arnulf H. Hölscher, University of Cologne, Germany and others)

Chapter VI. Histological and Serological Tumor Markers of Gastric Cancer;pp. 93-111
(Wataru Yasui, Kazuhiro Sentani, Naoya Sakamoto, Junichi Motoshita and Naohide Oue, University Graduate School of Biomedical Sciences,Japan)

Chapter VII. Colon Cancer;pp. 113-133
(Wendy L. Allen and Patrick G. Johnston, Queen's University,Belfast, Northern Ireland)

Chapter VIII. Predictors of Response of Rectal Cancer to Neoadjuvant Radiochemotherap;pp. 135-165
(Fraser M. Smith, J.V. Reynolds,St. James Hospital and Trinity College, Dublin, Ireland)

Chapter IX. Pancreas Cancer;pp. 167-214
(Giuseppe Tonini and Francesco Pantano, University Campus Bio-Medico,Rome, Italy)

Chapter X. Liver Cancer Biomarkers;pp. 215-237
(John M. Luk, Sarwat Fatima and Nikki P. Le, The University of Hong Kong, Pokfulam,Hong Kong)

Chapter XI. Prognostic and Predictive Immunohistochemical Tumor Markers in Breast Carcinoma;pp. 239-266
(Tibor Tot and Dan Hellber, Center for Clinical Research, Falun,Sweden)

Chapter XII. Emerging Tumor Markers in Endometrial Cancer;pp. 267-179
(Alessandro D. Santin, Yale University, School of Medicine, New Haven,CT)

Chapter XIII. The P2X7: A Novel Biomarker to Differentiate Normal and Cancer Uterine Epithelial Cells;pp. 281-295
(George I. Gorodeski, Case Western Reserve University, Cleveland,Ohio)

Chapter XIV. Tumor Markers in Cervical Cancer and and Preinvasive Neoplasia (CIN;pp. 297-340
(Dan Hellbeg, Uppsala University, Uppsala,Sweden)

Chapter XV. Histological and Serological Tumor Markers and Their Clinical Usefulness in Cancer: Cancer of the Ovary;pp. 341-379
(Maria Rosaria Raspollini, University of Florence, Italy)

Chapter XVI. Biomarkers in Penile Cancer;pp. 381-399
(Fernando Augusto Soares, Isabela Werneck da Cunha and Gustavo Cardoso Guimarãe, University of Sao Paulo, Brazil and others)

Chapter XVII. Established and Future Diagnostic and Prognostic Markers in Prostate Cancer;pp. 401-439
(T. Schlomm, T. Steuber, S. Minner, A. Haese and J. Köllermann, University Medical Center Hamburg-Eppendorf, Hamburg, Germany)

Chapter XVIII. HIV Infection and Related Malignancies;pp. 441-467
(Amos D. Mwaka, Victoria Walusansa-Abaliwano, Warren Phipps and Jackson Orem, Makerere University School of Medicine, Kampala,Uganda and others)

Chapter XIX. Summary and Conclusion;pp. 469-476
(Dan Hellberg and Michael J. Duffy, Upsala University, Uppsala, Sweden and others)

Index