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Handbook of Hematology Research: Hemorheology, Hemophilia and Blood Coagulation
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Editors: Rémi Tondre and Charles Lebčgue
Book Description:
Hematology is the branch of medicine that deals with diseases of the blood and blood-forming organs. Hemophilia is one of the most important diseases of hematology research. Medically, the classical treatment of hemophilia is transfusion therapy, which has been widely used for years. However, the transfusion can bring several complications for hemophiliac patients, such as the onset of blood borne infectious diseases. This book discusses such diseases, as well as the new trend in blood product safety management. Until present, the new modality of gene therapy is the hope for successfully treating hemophilia. The authors of this book briefly review and discuss this new hemophilia treatment. In addition to examining the etiology, pathogenesis and treatment of hemophilia, the factors involved in the activation of blood coagulation are examined as well. Other chapters in this book explore the immune responses and induction of immune tolerance to FVIII/FIX in hemophilia gene transfer, the haemostatic changes in complicated pregnancy states like preeclampsia and pregnancy-induced hypertension, a review of the new routine parameters for diagnosis of the early phases of pathologic disseminated intravascular coagulation (PDIC), and the quantitative and qualitative congenital plasminogen defects of the fibrinolytic system.

Table of Contents:
Preface

Chapter I. Congenital Defects of the Fibrinolytic System
(Sartori Maria Teresa, Department of Cardiac, Thoracic and Vascular Sciences, Padua, Italy), pp. 1-32

Chapter II. Blood Coagulation Fuels Inflammation,
Implementing a Blood Coagulation-Inflammation-Thrombosis Circuit
(Dr. Arthur J. Chu, Biological & Physical Sciences, Delta State University, Cleveland, MS)^, pp. 33-86

Chapter III. New Methods for Studying Platelets and Red Blood Cells, Based Upon the Low-Angle Light Scattering Technique
(Igor V. Mindukshev, Elena Yu. Senchenkova, Nikolay V. Goncharov, Elena V. Vivulanets, Vladimir V. Krivoshlyk, I.M. Sechenov Research Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Sciences, St. Petersburg, Russia, and others), pp. 87-124

Chapter IV. Immune Tolerance Induction in Hemophilia Gene Therapy
(Arpita S. Bharadwaj and Hengjun Chao, Division of Hematology/Oncology, Department of Medicine, Immunology Institute, Mount Sinai School of Medicine, New York, NY), pp. 125-144

Chapter V. Haemostatic Status in Normal and Complicated Pregnancies
(Stephen C.L. Koh, National University of Singapore, Yong Loo Lin School of Medicine, Department of Obstetrics and Gynaecology, National University Hospital, Singapore), pp. 145-178

Chapter VI. Neutrophil Granulocytes in Hemostasis
(Thomas W. Stief, Institute of Clinical Chemistry, University Hospital Giessen and Marburg, Marburg, Germany), pp. 179-200

Chapter VII. Recent Developments in the Management of Hemophilia A with Inhibitors
(Peter Kubisz, Jan Stasko, Pavol Holly—National Hemostasis and Thrombosis Centre, Clinic of Hematology and Transfusiology, Jessenius Faculty of Medicine of the Comenius University, Faculty Hospital, Martin, Slovakia), pp. 201-218

Chapter VIII. Ambulatory Hemorheology Monitoring and its Impact on Healthcare Utilization in a Public Hospital
(Jong Yong Abdiel Foo, Siddhartha Sanyal, Division of Research, Singapore General Hospital, Singapore, and others), pp. 219-236

Chapter IX. Arterial Hemodynamics and Pulse Wave Physiology
(Korpas David, Department of Medical Biophysics, Faculty of Medicine, Palacky University Olomouc, the Czech Republic), pp. 237-254

Chapter X. The Laboratory Diagnosis of the Pre-Phase of Pathologic Disseminated Intravascular Coagulation
(Thomas W. Stief, Department of Clinical Chemistry, University Hospital Giessen & Marburg, Germany), pp. 255-270

Chapter XI. Hemophilia Treatment: From Factor Transfusion to Gene Therapy
(Viroj Wiwanitkit, Wiwanitkit House, Bangkhae, Bangkok Thailand), pp. 271-280

Chapter XII. Hemophilia: Etiology, Pathogenesis and Treatment
(Emérito Carlos Rodriguez-Merchan, Department of Orthopaedics and Hemophilia Unit, La Paz University Hospital, Madrid, Spain, and others), pp. 281-292

Chapter XIII. Blood Borne Infections in Hemophilia
(Viroj Wiwanitkit, Wiwanitkit House, Bangkhae, Bangkok Thailand), pp. 293-302

Chapter XIV. Effects of Exercise on Blood Coagulation Activity in Sickle Cell Trait Carriers: Abnormalities or Not?
(Philippe Connes, Eric Beltan, Tawfik Chalabi and Julien Tripette, Laboratoire ACTES, Département de Physiologie, Université des Antilles et de la Guyane, Campus de Fouillole, Guadeloupe, and others), pp. 303-310

Chapter XV. Managing Acquired Hemophilia Viewed by Practical Cases
(Takatoshi Koyama, Laboratory Molecular Genetics of Hematology, Graduate School of Health Sciences, Tokyo Medical and Dental University, Tokyo, Japan), pp. 311-316

Chapter XVI. Disorders of the Haemostatic System in Patients with Solid Malignancies (Géza, Bozóky and Éva, Ruby, Department of Pulmonology, Municipal Hospital of Bács-Kiskun County, Kecskemét, Hungary), pp. 317-318

Index, pp. 319

   Series:
      Recent Advances in Hematology Research
   Binding: Hardcover
   Pub. Date: 2011
   Pages: 7 x 10, 345 pp.
   ISBN: 978-1-60741-619-7
   Status: AV
  
Status Code Description
AN Announcing
FM Formatting
PP Page Proofs
FP Final Production
EP Editorial Production
PR At Prepress
AP At Press
AV Available
  
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Handbook of Hematology Research: Hemorheology, Hemophilia and Blood Coagulation