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Developments in Stem Cell Research $130.00
Editors: Prasad S. Koka (Laboratory of Stem Cell Biology, Torrey Pines Institute for Molecular Studies, USA)
Book Description:
The two broad categories of mammalian stem cells exist: embryonic stem cells, derived from blastocysts, and adult stem cells, which are found in adult tissues. In a developing embryo, stem cells are able to differentiate into all of the specialised embryonic tissues. In adult organisms, stem cells and progenitor cells act as a repair system for the body, replenishing specialised cells.
As stem cells can be readily grown and transformed into specialised tissues such as muscles or nerves through cell culture, their use in medical therapies has been proposed. In particular, embryonic cell lines, autologous embryonic stem cells generated therapeutic cloning, and highly plastic adult stem cells from the umbilical cord blood or bone marrow are touted as promising candidates.
Among the many applications of stem cell research are nervous system diseases, diabetes, heart disease, autoimmune diseases as well as Parkinsonís disease, end-stage kidney disease, liver failure, cancer, spinal cord injury, multiple sclerosis, and Alzheimerís disease. Stem cells are self-renewing, unspecialized cells that can give rise to multiple types all of specialized cells of the body. Stem cell research also involves complex ethical and legal considerations since they involve adult, fetal tissue and embryonic sources. This new book presents the latest research in the field from around the globe.

Table of Contents:
Preface

1. Human Embryonic Stem Cells Undergo Osteogenic Differentiation in Human Bone Marrow Stromal Cell Microenvironments pp.1-12
(Wilbur Tong, Shelley E Brown and Paul H Krebsbach)

2. Hyaluronic Acid Promotes Osteochondrogenic Differentiation from Mesenchymal Stem Cells in a Three-Dimensional Culture System pp.13-24
(Kiyoshi Yoneno, Eiji Tanaka, Shigeru Ohno, Kotaro Tanimoto, et.al.)

3. Cell Cycle Regulation in Maintaining Immortality of Embryonlic Stem Cells pp.25-36
(Rajarshi Pal, Ashish Mehta and Aparna Khanna)

4. Potential Target Molecules for Ex Vivo Expansion of Hematopoietic Stem Cells and Their Roles in Normal Hematopoiesis pp.37-58
(Hirokazu Tanaka, Itaru Matsumura and Yuzuru Kanakura)

5. Autotransplantation of Purified Mensenchymal Stem Cells in a Patient with Acute Myocardial Infarction: A Case Study pp.59-66
(Zhen-Xing Zhanga, Yan-Zhen Zhangb, Li-Xue Guanc, Long-Jun Dai, et.al.)

6. Human Telomerase Catalytic Subunit (hTERT)-Transfected Mesenchymal Stem-Like Cells Derived from Fetal Liver Promote Ex Vivo Expansion of Hematopoietic Stem Cells pp.67-84 (Yu-xia Yang, Zhen-chuan Miao, Hao-jian Zhang, Yun Wang and Mei-fu Feng)

7. Searching for Bone Marrow-Derived Cells in Experimental Models for Renal Injury: Reporter Systems Revisited pp.85-102 (Martine Broekema, Martin C. Harmsen and Eliane R. Popa)

8. The Regulatory Function of MicroRNA in Stem Cells pp.103-112 (Wei Wu, Vivien Wang and Gang-Ming Zou)

9. Niche Theory, Stem-Stromal Imbalance and Aplastic Anaemia pp.113-126(Sujata Law, Samaresh Chaudhuri)

10. Natural Killer Cell Receptor NKG2A/HLA-E Interaction Dependent Differential Thymopoiesis of Hematopoietic Progenitor Cells Influences the Outcome of HIV Infection pp.127-142
(Edmond J. Yunis, Viviana Romero and Prasad Koka

Index pp.143-160

   Series:
      Stem Cells - Laboratory and Clinical Research
   Binding: ebook
   Pub. Date: 2008
   Pages: pp.160
   ISBN: 978-1-60741-213-7
   Status: AV
  
Status Code Description
AN Announcing
FM Formatting
PP Page Proofs
FP Final Production
EP Editorial Production
PR At Prepress
AP At Press
AV Available
  
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