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Hippocampus: Anatomy, Functions and Neurobiology
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Editors: Ambroise Gärtner and Dener Frantz
Book Description:
A peculiar feature of the mammalian hippocampus is that it maintains the ability to generate new neurons throughout adult life while most other areas of the brain do not. In this book, we outline evidence for the functional consequences of adult neurogenesis in the dentate gyrus highlighting a possible role in learning and memory and depression. Presynaptic modulation at the MF synapse is also described with respect to its involvement in the activity-dependent nature of the MF synapse and contribution to physiological functions of MFs. In addition, the hippocampus is one of the first and most affected brain regions impacted by both Alzheimer’s disease and mild cognitive impairment. This book discusses such negative consequences of aging and diseases which may be prevented or reversed by physical exercise, which has been associated with improved hippocampul-dependent learning and memory and executive functioning. The functional status of hippocampal cholinergic terminals was also assessed in order to determine if an early beginning of ethanol consumption at moderate doses disrupts acetylcholine release in animals non selected by ethanol preference.

Table of Contents:

Chapter 1. Long-Term Effects of Prenatal Alcohol Exposure on the Hippocampal Anatomy and Functions;pp. 1-29
(Joanna H. Sliwowska, University of British Columbia, Department of Cellular and Physiological Sciences, Vancouver, Canada)

Chapter 2. The Putative Role of Neurogenesis in the Hippocampus of Adult Rodents: Emphasis on Cognition and Depression;pp. 31-55
(Jonathan R. Epp, Steven R. Wainwright, Liisa A.M. Galea, Department of Psychology, University of British Columbia, Vancouver, Canada)

Chapter 3. Presynaptic Modulation at the Mossy Fiber Synapse;pp. 57-82
(Katsunori Kobayashi, Department of Pharmacology, Nippon Medical School, Tokyo, Japan)

Chapter 4. Evidence for a Spiral Organization of Information Flow through the Hippocampal Formation;pp. 83-108
(Nikolay A. Vorobyov, Malcolm W. Brown, MRC Centre for Synaptic Plasticity, Department of Anatomy, University of Bristol, Bristol, UK)

Chapter 5. The Physiopathology of Hippocampal Degenerative Process in Mild Cognitive Impairment and Alzheimer’s disease as Revealed by Scalp EEG Activity;pp. 109-123
(D.V. Moretti, G.B. Frisoni, G. Binetti, Giovanni DeGirolamo, P.M. Rossini, O. Zanetti, IRCCS S. Giovanni di Dio Fatebenefratelli, Brescia, Italy, and others)

Chapter 6. Neurobiology of Exercise: A Behavioral Intervention to Enhance Hippocampal Function and Plasticity;pp. 125-137
(Aderbal S. Aguiar Jr., Laboratório Experimental de Doenças Neurodegenerativas, Departamento de Farmacologia, Universidade Federal de Santa Catarina – UFSC, Florianópilis, Brazil)

Chapter 7. Early Beginning of Ethanol Consumption at Moderate Doses Did Not Impair Hippocampal Acetylcholine Release;pp. 139-145
(Noemi Robles, Josefa Sabriá, Institut de Neurociències, Dept. Bioquímica i Biologia Molecular, Universitat Autònoma de Barcelona, Barcelona, Spain)

Chapter 8. Involvement of Zinc via Crosstalk with Calcium in Synaptic Plasticity and Neurodegeneration in the Hippocampus;pp. 147-166
(Atsushi Takeda, Dept. of Medical Biochemistry, School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, Japan)*

Chapter 9. Inhibitory Effects of Aβ-amyloid Aggregates on Synaptic Transmission in Hippocampal Neurons;pp. 167-179
(L.G.Aguayo, J. Parodi, F.J. Sepúlveda,J. Roa, C. Opazo,
Universidad de Concepción, Chile)*


      Neuroanatomy Research at the Leading Edge
   Binding: Hardcover
   Pub. Date: 2010
   Pages: 7 x 10, 196 pp.
   ISBN: 978-1-60876-225-5
   Status: AV
Status Code Description
AN Announcing
FM Formatting
PP Page Proofs
FP Final Production
EP Editorial Production
PR At Prepress
AP At Press
AV Available
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Hippocampus: Anatomy, Functions and Neurobiology