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Huntington's Disease: Etiology and Symptoms, Diagnosis and Treatment $265.00
Editors: Thomas J. Visser
Book Description:
Huntington's disease, chorea or disorder (HD) is an incurable neurodegenerative genetic disorder, which affects muscle coordination and some cognitive functions, typically becoming noticeable in middle age. It is the most common genetic cause of abnormal involuntary writhing movements called chorea and is much more common in people of Western European descent than in those from Asia or Africa. The disease is caused by a dominant mutation on either of the two copies of a gene called Huntington. This book gathers and presents current research in the study of Huntington's Disease including the outlining effects of mutant htt in the nucleus and cytoplasm and the role of cell-cell interactions in Huntington's Disease pathology, as well as a review of the role of Huntington (HTT) interacting proteins.

Table of Contents:

Molecular Mechanisms Involved in the Pathogenesis of Huntington’s Disease
(Claudia Perandones, Martin Radrizzani, Federico Eduardo Micheli, Movement Disorders and Parkinson´s Disease Program, Hospital de Clínicas, José de San Martín, University of Buenos Aires, Buenos Aires, Argentina, and others)

Huntingtin Interacting Proteins: Involvement in Diverse Molecular Functions, Biological Processes and Pathways
(Moumita Datta, Manisha Banerjee, Srijit Das, Nitai P. Bhattacharyya, Crystallography and Molecular Biology Division and Structural Genomics Section, Saha Institute of Nuclear Physics, Kolkata, India)

DNA Repair and Huntington’s Disease
(Fabio Coppedč, Department of Neuroscience, University of Pisa, Pisa, Italy)

Putting Together Evidence and Experience: Best Care in Huntington’s Disease
(Paola Zinzi, Gioia Jacopini, Marina Frontali, Anna Rita Bentivoglio, Consiglio Nazionale delle Ricerche, Istituto di Neurobiologia e Medicina Molecolare & Istituto di Scienze e Tecnologie della Cognizione, Rome, Italy, and others)

Oral Health Care for the Individual with Huntington’s Disease
(Robert Rada, Department of Oral Medicine and Diagnostic Sciences, University of Illinois College of Dentistry, Illinois)

Suicidal Ideation and Behaviour in Huntington’s Disease ^
(Tarja-Brita Robins Wahlin, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden)

Making Reproductive Decisions in the Face of a Late-Onset Genetic Disorder, Huntington’s Disease: An Evaluation of Naturalistic Decision-Making Initiatives
(Claudia Downing, Centre for Family Research, Cambridge University, Cambridge, England)*

The Control of Adult Neurogenesis by the Microenvironment and How this May be Altered in Huntington’s Disease
(Wendy Phillips, Roger A. Barker, Cambridge Centre for Brain Repair, Cambridge, England, and others)*


      Neuroscience Research Progress
   Binding: ebook
   Pub. Date: 2010
   Pages: 7 x 10
   ISBN: 978-1-61728-451-9
   Status: AV
Status Code Description
AN Announcing
FM Formatting
PP Page Proofs
FP Final Production
EP Editorial Production
PR At Prepress
AP At Press
AV Available
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Huntington's Disease: Etiology and Symptoms, Diagnosis and Treatment