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Human Spermatozoa: Maturation, Capacitation and Abnormalities $395.00
Editors: Thomas Lejeune and Pascal Delvaux
Book Description:
Spermatozoa is the basic human male germ cell. This gametocyte plays an important role in fertilization. In the past five years, new improvements in diagnosis have allowed us to assess male fertility potential with a new perspective studying with demonstrated role in sperm physiology. Furthermore, it is demonstrated that infertile men have high levels of sperm DNA damages and a small percentage of spermatozoa from fertile men also possess detectable levels of DNA damage. This book examines several of the factors that may be involved in sperm chromatin and DNA anomalies, including intra and extra testicular factors. Furthermore, sperm capacitation is a complex physiological process that involves biochemical, biophysical, molecular and metabolic modifications of all sperm domains. Some important events related to the capacitation process of sperm is examined as well. The biological role of the proteasome during sperm capacitation and the acrosome reaction and its relationship with protein phosphorylation and dephosphorylation during these processes is explored as well. Other chapters in this book highlight the pivotal role of transmission electron microscopy (TEM) analysis in the diagnosis of human sperm pathologies, the barrier methods currently available to men for regulating their fertility, a discussion of the current understanding of gene transfer to the testis, a new perspectives for the study of mycoplasmal and chlamydial infections of human spermatozoa and a discussion of the present current knowledge on the mechanisms, molecules and cell signaling involved in sperm activating ability.

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Table of Contents:

Sperm Nuclear Maturation: A Basic and Clinical Approach pp.1-86
(Talebi, Ali Reza (A. R.), Department of Biology and Anatomical Sciences, Research & Clinical Center for Infertility, Shahid Sadoughi Medical University, Yazd, Iran)

Sperm Capacitation: Physiology, Molecular Mechanisms and Relevance for Fertilization pp.87-122
(Rita de Cássia da Silveira e Sá, Reproduction Biology Center/Biology Department, Federal University of Juiz de Fora, Juiz de Fora, MG, Brazil)

Role of the Human Sperm Proteasome during Capacitation and the Acrosome Reaction: Interaction with Protein Kinases and Phosphatases pp.123-154
(Janetti Signorelli, Emilce S. Diaz, Patricio Morales, Department of Biomedicine, Faculty of Health Sciences, University of Antofagasta, Antofagasta, Chile)

Development and Maturation of Human Germ Cells and Disorders of Those Processes in Childhood pp.155-182
(Zivkovic Dragana, Hadziselimovic Faruk, Institute for Child and Youth Health Care of Vojvodina, Novi Sad, Serbia, and others)

Family Planning, Male Contraception, and Reproductive Health pp.183-204
(Daulat R.P. Tulsiani, Departments of Obstetrics & Gynecology, and Cell & Developmental Biology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA)

Effects of the Seminal Plasma Proteins Semenogelin (SEMG)/Seminal Vesicle Secretion 2 (SVS2) on Sperm Fertility pp.205-220
(Kaoru Yoshida, Teruaki Iwamoto, and Manabu Yoshida, Biomedical Engineering Center, Toin University of Yokohama, Yokohama 225-8502, Japan)

Gene Therapy for Male Infertility: Potential and Limitation pp.221-242
(Yoshiyuki Kojima, Kentaro Mizuno, Shoichi Sasaki, Yutaro Hayashi, Kenjiro Kohri, Department of Nephro-urology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan)

Capacitation and Acrosome Reaction pp.243-262
(Fábio F. Pasqualotto, Luana Venturin Lara, Eleonora Bedin Pasqualotto, Instituto de Biotecnologia e Centro de Ciências da Saúde, Universidade de Caxias do Sul, RS and CONCEPTION – Centro de Reprodução Humana, Caxias do Sul, RS, Brasil)

Impaired Function of the Spermatozoa: Links with Mycoplasmal and Chlamydial Infections pp.263-286
(Díaz-García Francisco Javier, Flores-Medina Saul, Giono-Cerezo Silvia, Departamento de Salud Pública, Facultad de Medicina, Universidad Nacional Autónoma de México, México, and others)

Clinic Management of Men with Macrocephalic Sperm Head Syndrome pp.287-306
(Kahraman Semra, Candan ZN, Memorial Hospital ART & Reproductive Genetics Centre, Istanbul, Turkey)

Mitochondria and Spermatozoa pp.307-326
(Pascale May-Panloup, Yves Malthiery, Pascal Reynier, Département de Pathologie Cellulaire et Tissulaire, Centre Hospitalier Universitaire, Angers, France, and others)

Recent Insights into Spermatozoa Development and Ultrastructure in the Eucestoda pp.327-354
(Magdaléna Bruňanská, Parasitological Institute, Slovak Academy of Sciences, Košice, Slovak Republic)

The Use of Pentoxifylline for Triggering the Movement of Testicular Sperm before their Use in Intracytoplasmic Sperm Injection in Men with Azoospermia pp.355-378
(Borut Kovacic, Veljko Vlaisavljevic, Department of Reproductive Medicine and Gynecologic Endocrinology, University Clinical Centre Maribor, Slovenia)

Sperm Induced Oocyte Activation pp.379-398
(Elisabetta Tosti, Yves Ménézo, Laboratory of Animal Physiology and Evolution, Stazione Zoologica, Naples, Italy, and others)

DNA Integrity and mRNA Expression Profile as Indicators of Sperm Quality and Assisted Reproduction Outcome pp.399-418
(Marcos Meseguer, Sandra García-Herrero, Thamara Viloria, Rebeca Santiso, Jose Luis Fernández, Nicolás Garrido, Instituto Valenciano de Infertilidad,,Universidad de Valencia, Valencia, Spain, and others)

Concern about the Possibility of Seminal Quality Decline in World Men Population pp.419-432
(Andrea Giannotti Galuppo, Roseli Fernandes Gonçalves, Embryology and Animal Reproduction Biotech Laboratory, College of Veterinary Medicine, Rio Grande do Sul Federal University, RS, Brazil, and others)

Sperm in Seropositive Males for HIV or HCV pp.433-448
(Nicolás Garrido, José Remohí, José Bellver, Marco A. Melo-Barreto, Antonio Pellicer, Marcos Meseguer, Instituto Universitario IVI, Universidad de Valencia, Valencia, Spain, and others)

The Heterochromatic Component of the Human Y Chromosome: A Genetic Wasteland or Something More? Suggestions from the Fruitfly pp.449-462
(Roberto Piergentili, Sapienza – Università di Roma, Department of Genetics and Molecular Biology, Rome; Italy)

Maintenance of the Cryopreserved Sperm in the Fertility Clinic is a Risky Task: Precautionary Note for the Clinics pp.463-472
(Amjad Hossain, John Phelps, Department of Obstetrics and Gynecology, University of Texas Medical Branch, Galveston, Texas, USA)

Integrins in Human Spermatozoa: Their Role in Fertilization Process pp.473-482
(Roseli Fernandes Gonçalves, Andrea Giannotti Galuppo, Valquiria Hyppolito Barnabe, Department of Animal Reproduction, College of Veterinary Medicine and Animal Sciences, São Paulo University, São Paulo, SP, Brazil, and others)

Heavy Metal Contaminants and Male Reproductive Health pp.483-490
(Debjani Nath, Department of Zoology, University of Kalyani, West Bengal, India)

Interactions between Visible Light and Sperm Cells pp.491-500
(Rachel Lubart, Departments of Chemistry and Physics, Bar-Ilan University, Ramat-Gan, Israel)

Energy Consumption in Semen due to the Protein Glycosylation in Poorly Controlled Diabetes Mellitus pp.501-506
(Viroj Wiwanitkit, Wiwanitkit House, Bangkhae, Bangkok, Thailand)

Spermatozoa in Zero Gravity Space: A New Concern pp.507-510
(Viroj Wiwanitkit, Wiwanitkit House, Bangkhae, Bangkok, Thailand)

Estrogen Usage in Gay: Effect on Spermatozoa? pp.511-514
(Viroj Wiwanitkit, Wiwanitkit House, Bangkhae, Bankgok Thailand)

Index pp.515-545

      Human Reproductive System - Anatomy, Roles and Disorders
   Binding: ebook
   Pub. Date: 2010
   Pages: pp.545
   ISBN: 978-1-61470-060-9
   Status: AV
Status Code Description
AN Announcing
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PP Page Proofs
FP Final Production
EP Editorial Production
PR At Prepress
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Human Spermatozoa: Maturation, Capacitation and Abnormalities