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TRP Channels in Health and Disease: Implications for Diagnosis and Therapy $330.00
Editors: Arpad Szallasi (Monmouth Medical Center, Long Branch, NJ, USA)
Book Description:
Changes in temperature, either hot or cold, is sensed through direct activation of members of the temperature-sensitive transient release potential (TRP) ion channel superfamily, the so-called “thermoTRPs”. Of the 28 TRP channels discovered today, seven sense hot or warm temperatures whereas two are activated by cold. Together, these channels cover a wide temperature range with extremes that fall between 10 C and 53 C. This new and unique book reviews research on TRP channels and their relation to health and disease.

Table of Contents:
(Arpad Szallasi, Department of Pathology, Monmouth Medical Center, Long Branch, NJ, USA)

1. TRP Channels in Health and Disease: An Overview; pp. 1-16
(Gina Story, Pain Center, Washington University School of Medicine, St. Louis, MO, USA)

2. TRP Channelopathies; pp. 17-38
(Bernd Nilius and Grzegorz Owsianik, Department of Molecular Cellular Biology, Catholic University, Leuven, Belgium)

3. TRP Polymorphism; pp. 39-50
(Hyungsuk Kim, Michael J. Iadarola and Ray A. Dionne, National Institute of Nursing Research and National Institute of Dental and Craniofacial Research, NIH, Bethesda, MD, USA)

4. Complex Regulation of TRP Channels by PIP2; pp. 51-72
(Tibor Rohacs, Department of Pharmacology, UMDNJ – New Jersey Medical School, Newark, NJ, USA)

5. TRP Channel Trafficking; pp. 73-86
(Rosa Planells-Cases, María Camprubí-Robles and Antonio Ferrer-Montiel, Instituto de Biología Molecular y Celular, Universidad Miguel Hernández, Alicante, Spain)

6. Disease-Related Changes in TRP Channel Expression: Clinical Studies; pp. 87-102
(Ravikiran Shenoy, Katherine Roberts and Praveen Anand, Department of Clinical Neuroscience, Imperial College, London, UK)

7. Targeting Supraspinal TRP Channels for Pain Relief; pp. 103-120
(Enza Palazzo, Vito de Novellis, Francesca Rossi and Sabatino Maione, Department of Experimental Medicine, University of Naples, Italy)

8. Role of Transient Receptor Potential Channels in Thermosensation and Thermoregulation; pp. 121-152
(Marcello Trevisani and Arpad Szallasi, Pharmeste, Ferrara, Italy and Department of Pathology, Monmouth Medical Center, Long Branch, NJ, USA)

9. TRP Channels and Osmoregulation; pp. 153-170
(Wolfgang Liedtke, Center for Translational Neuroscience, Duke University School of Medicine, Durham, NC, USA)

10. TRP Channels and Blood Pressure Regulation; pp. 171-196
(Ryuji Inoue and Juan Shi, Department of Physiology, Fukuoka University School of Medicine, Fukuoka, Japan and Department of Anatomy and K.K. Leung Brain Research Centre, the Fourth Military Medical University, China)

11. TRP Channels in Feeding and Body Weight; pp. 197-208
(Arianne L. Motter and Gerard Ahern, Department of Pharmacology, Georgetown University, Washington DC, USA)

12. TRP Channels and Cancer; pp. 209-222
(Dimitra Gkika and Natalia Prevarskaya, INSERM U800, Laboratorie de Physiologie Cellulaire, USTL, Université de Lille, France)

13. Transient Receptor Potential Channels in Kidney; pp. 223-242
(Paolo Mené, Giorgio Punzo and Nicola Pirozzi, Department of Clinical Sciences, “Sapienza” University of Rome, 2nd Medical School, Division of Nephrology. Sant’Andrea University Hospital, Rome, Italy)

14. TRP Channels in the Urinary Bladder and Prostate: Implications for Therapy; pp. 243-258
(Ana Charrua and Francisco Cruz, Institute of Histology and Embryology, Faculty of Medicine of Porto, Porto, Portugal; Instituto de Biologia Molecular e Cellular, Universidade do Porto, Porto, Portugal; and Department of Urology, Hospital São João and Faculty of Medicine, Porto, Portugal)

15. TRP Channels in the Gastrointestinal Tract; pp. 259-290
(Peter Holzer, Research Unit of Translational Neurogastroenterology, Institute of Experimental and Clinical Pharmacology, Medical University of Graz, Austria)

16. TRP Channels and Airway Diseases; pp. 291-316
(Riccardo Patacchini and Maurizio Civelli, Preclinical R&D Department, Chiesi Farmaceutici, Parma, Italy)

17. TRP Channels and Migraine; pp. 317-330
(Francesco De Cesaris, Silvia Benemei, Paola Nicoletti, Jay G. Capone and Pierangelo Geppetti, Headache Center, University Hospital Careggi, and Department of Preclinical and Clinical Pharmacology, University of Florence, Florence, Italy and others)

18. TRP Channels in Cutaneous Biology in Health and Disease; pp. 331-362
(Tamás Bíró and Ralf Paus, Department of Physiology, University of Debrecen, Research Center for Molecular Medicine, Debrecen, Hungary and Department of Dermatology, University Hospital Schleswig-Holstein, Lübeck, Germany)

19. TRP Channels in Neurodegenerative Disease and Stroke; pp. 363-392
(Matthew McNeill and Robert A. Cornell, Interdisciplinary Graduate Program in Neuroscience, University of Iowa, Iowa City, IA, USA and Department of Anatomy and Cell Biology, carver College of Medicine, University of Iowa, Iowa City, IA, USA)

20. TRP Channels in Brain: Psychiatric Disorders; pp. 393-414
(Loris A. Chahl, Centre for Brain and Mental Health Research, University of Newcastle, and Schizophrenia Research Institute, NSW, Australia)

21. Role of TRP Channels in Drug Dependence; pp. 415-424
(Manish Rautham and X.Z. Shawn Xu, Life Sciences Institute and Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, USA)

22. TRP Channels and Sepsis; pp. 425-440
(Elizabeth S. Fernandes, Gabor Pozsgai and Susan D. Brain, Cardiovascular Division, Department of Pharmacology, King’s College, London, UK)

23. Targeting TRP Channels: An Overview of Current Drug Discovery efforts and future directions; pp. 441-472
(Samer R. Eid, Eric D. Crown and Mark O. Urban, Department of Pain Research, Neuroscience Drug Discovery, Merck Research Laboratories, Philadelphia, PA, USA)

24. TRPV1 Agonists in Clinical Trials for Pain; pp. 473-490
(Christopher Noto and Marco Pappagallo, Department of Anesthesiology, Division of Pain Medicine, Mount Sinai School of Medicine, New York, USA)

25. TRPV1 antagonists in Clinical Trials; pp. 491-514
(Martin J. Gunthorpe and Boris A. Chizh, Neurociences Centre of Excellence for Drug Discovery, GlaxoSmithKline, Harlow, Essex, UK; Clinical Pharmacology, GlaxoSmithKline, Addenbrooke’s Centre for Clinical Investigation, Cambridge, UK)

26. Concluding Remarks and Future Directions; pp. 515-534
(Shaya Lev and Baruch Minke, Department of Physiology and the Kühne Minerva Center for Studies of Visual Transduction, Faculty of Medicine, The Hebrew University, Jerusalem, Israel)

Index; pp. 535-563

      Medicine and Biology Research Developments (Series Editor - Tsisana Shartava, M.D. - Tbilisi, Georgia)
   Binding: ebook
   Pub. Date: 2011 3rd Quarter
   Pages: 7 x 10
   ISBN: 978-1-62081-812-1
   Status: AV
Status Code Description
AN Announcing
FM Formatting
PP Page Proofs
FP Final Production
EP Editorial Production
PR At Prepress
AP At Press
AV Available
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TRP Channels in Health and Disease: Implications for Diagnosis and Therapy