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Copolymers in the Preparation of Parenteral Drug Delivery Systems
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Authors: Rossella Dorati, Claudia Colonna, Ida Genta, Tiziana Modena and Bice Conti (University of Pavia, Pavia, Italy) 
Book Description:
Poly orthoesters have been the most intensively studied polymers for biomedical applications for their low immunogenicity, good biocompatibility and excellent mechanical properties. In the last decade, the synthesis of polyester-polyether block copolymers has attracted increasing attention, because they may be used in several pharmaceutical and medical applications such as sutures, implants for bone fixation, carriers in drug delivery and temporary matrix or scaffolds in tissue engineering. This book includes the last two decades when block copolymers containing PEO, hydrophilic B-blocks, and PLA or PLGA, hydrophobic A-blocks, have been widely utilized to formulate parenteral drug delivery systems for peptides and proteins, such as micro and nanoparticles, implants, micelles, hydrogels and scaffolds.


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Table of Contents:
Preface pp. i-xi
Abbreviations
Introduction

Chapter 1. Definition and Classification of Block Copolymers,
pp. 7-9

Chapter 2. Synthesis of Block Copolymers from PEO and Lactones,
pp. 11-13

Chapter 3. Mechanism of Copolymerization from PEO and Lactone,
pp. 15-20

Chapter 4. Physico-Chemical Properties of Block Copolymers from PEO and Lactones,
pp. 21-24

Chapter 5. Degradation of ABA Triblock Copolymers based on PEO and Polyesters,
pp. 25-30

Chapter 6. Parenteral Drug Delivery Systems based on ABA Polymers, pp. 31-49

Chapter 7. Overview on Sterilization Techniques for Block Copolymers, pp. 51-61

Chapter 8. Conclusion,
pp. 63

References
Index pp. 81-90

   Series:
      Polymer Science and Technology
   Binding: Softcover
   Pub. Date: 2012- December
   Pages: 101, 6 x 9
   ISBN: 978-1-61668-678-9
   Status: AV
  
Status Code Description
AN Announcing
FM Formatting
PP Page Proofs
FP Final Production
EP Editorial Production
PR At Prepress
AP At Press
AV Available
  
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Copolymers in the Preparation of Parenteral Drug Delivery Systems