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Brain Glucosensing: Physiological Implications
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Authors: Sergio Polakof (Universidade de Vigo, Spain) 
Book Description:
Glucose is an integral part of whole-body energy homeostasis and is tightly regulated by numerous endocrine, neuronal and behavioural systems, which ensure that glucose levels in the blood are maintained within a narrow physiological range. The body continuously adapts its metabolism to keep blood glucose concentrations at a constant value. Glucose homeostasis in man and most other studied mammals is maintained by feedback designed to keep the blood glucose levels close to a set point characteristic for each species. Key to this homeostatic control is the existence of sensors located in different parts of the body that continuously monitor blood glucose variations. They respond to changes in glycemia by triggering hormonal secretion or activation of the autonomic nervous system to control glucose uptake, utilization or production and also to control energy expenditure and food intake. This book examines brain glucosensing and its effect on the body. (Imprint: Nova Biomedical)




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Table of Contents:
1. Introduction pp.1-2

2. Glucose Metabolism in the Brain pp.3-4

3. Sites of Glucosensing in the Brain pp.5-8

4. The Glucosensor Mechanism in the Brain pp.9-16

5. Lactate as Metabolic Coupling between Astrocytes and Glucosensing Neurons pp.17-20

6. Network of Hypothalamic Glucosensing Neurons pp.21-24

7. The Mechanisms Underlying Glucosensing During Hypoglycemia pp.25-32

8. Brain Glucosensing and the Regulation of Food Intake and Energy Expenditure pp.33-36

9. Glucosensing Neurons as Metabolic Sensors pp.37-40

10. Conclusion pp.41-42

References pp.43-64

Index pp.65-69

   Series:
      Neurology - Laboratory and Clinical Research Developments
   Binding: Softcover
   Pub. Date: 2011
   Pages: 69.pp
   ISBN: 978-1-61761-334-0
   Status: AV
  
Status Code Description
AN Announcing
FM Formatting
PP Page Proofs
FP Final Production
EP Editorial Production
PR At Prepress
AP At Press
AV Available
  
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Brain Glucosensing: Physiological Implications