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New Developments in Antioxidants Research
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Editors: Harold V. Panglossi
Book Description:
In biological systems, the normal processes of oxidation (plus a minor contribution from ionizing radiation) produce highly reactive free radicals. These can readily react with and damage other molecules. In some cases the body uses free radicals to destroy foreign or unwanted objects, such as in an infection. However, in the wrong place, the body's own cells may become damaged. Should the damage occur to DNA, the result could be cancer. Antioxidants decrease the damage done to cells by reducing oxidants before they can damage the cell. Virtually all studies of mammals have concluded that a restricted calorie diet extends the lifespan of mammals by as much as 100%. This remarkable finding suggests that food is actually more damaging than smoking. As food produces free radicals (oxidants) when metabolized, antioxidant-rich diets are thought to stave off the effects of aging significantly better than diets lacking in antioxidants. The reduced levels of free radicals, resulting from a reduction in their production by metabolism, is thought to be a major cause of the success of caloric restriction in increasing life span.
Antioxidants consist of a group of vitamins including vitamin C, vitamin E, selenium and carotenoids, (such as beta-carotene, lycopene, and lutein). This new book brings together the latest research in this dynamic field.

Table of Contents:
Preface
Chapter 1- Reactive Oxygen Species and Dietary Antioxidants: Double-Edged Swords?, pp. 1-24;
(Harold Seifried, Darrell Anderson, John Milner and Peter Greenwald)

Chapter 2.- Methionine Redox Status as a Mediator of PrPc Function, pp. 25-41;
(W.M. Williams, Case Western Reserve University, USA and J. Moskovitz, University of Kansas, USA)

Chapter 3- Isothiocyanates as Promising Chemopreventive and Antioxidant Agents, pp. 43-59;
(Carmela Fimognari, Monia Lenzi, Giorgio Cantelli-Forti and Patrizia Hrelia)

Chapter 4- Novel Hydroxyphenylureas as Antioxidant and Chemopreventive Agents, pp. 61-79;
(Kharia M. Youssef, Magda El-Sherbeny, Faiza Elshafie, Omar Al-Deeb, Hassan H. Farag and Sit Albanat Awadalla)

Chapter 5- Oxidative and Nitrosative Stress in Human Aging: Age-Related Changes and Putative Mechanisms, pp. 81-111;
(Barbara Kłapcińska, Academy of Physical Education, Poland)

Chapter 6- Relationship of Structure and Antioxidant Activity of Synthetic Silybin- and Isosilybin Derived Molecules: Identification of Molecular Structure Responsible for Antioxidant Activity Employing Various Models for Inducing Oxidative Stress, pp. 113-151;
(Zsuzsa Varga, Emoke Nagy, Monika Katko, Viktoria Jeney, Laszlo Ujhelyi, Ildiko Seres, Gyorgy Paragh, Jozsef Ball and Sandor Antus)

Chapter 7- Measurements of Total Antioxidant Activity, pp. 153-175; (Chi Chiu Wang, Michael Scott Rodgers and Chi Pui Pang)
Index

   Binding: Hardcover
   Pub. Date: 2006
   ISBN: 1-59454-998-2
   Status: AV
  
Status Code Description
AN Announcing
FM Formatting
PP Page Proofs
FP Final Production
EP Editorial Production
PR At Prepress
AP At Press
AV Available
  
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New Developments in Antioxidants Research