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Translational Pain Research. Volume 1: Current Status and New Trends
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Editors: Jianren Mao (Mass. General Hospital, Harvard Medical School)
Book Description:
Basic science and clinical pain research is particularly challenging for several reasons. First, pain is a subjective experience in response to nociception that follows actual or potential tissue damage. Since the ability to respond to this warning signal is essential for our survival, the nociceptive system that produces and transmits nociceptive signals is remarkably redundant and involves diffuse regions of the central nervous system. Second, unlike other sensory modalities, pain is a multi-dimensional experience including at least cognitive, affective, and sensory-discriminative components. Third, pain experiences can be influenced by psychological, socioeconomic, cultural, and genetic predispositions, making it exceedingly complicated to study pain and pain modulation.
In this first volume, the current status and new trends of pain research are selectively discussed in order to take a critical and constructive look at the achievements of basic science research that have made significant differences in clinical pain management as well as the gaps between basic science research and clinical pain management.

Table of Contents:

Chapter 1. Theories of Pain;
pp. 1-27
(Donald D. Price, University of Florida, USA and Kenneth J. Sufka, University of Mississippi, USA)

Chapter 2. Spinal Cord Mechanisms of Pain and their Modulation;
pp. 29-165
(Lisa Thomson and Gregory Terman, University of Washington, USA)

Chapter 3. Long-Lasting Sensory Potentiation: A Synaptic Model for Central Pain;
pp. 167-180
(Min Zhou, University of Toronto, Canada)

Chapter 4. Molecular Pain and Pain Management;
pp. 181-198
(Jiango Gu, University of Florida, USA)

Chapter 5. A Dual-System Integration Model of Pain Mechanisms: Implications for Clinical Pain;
pp. 199-221
(Jianren Mao, Harvard Medical School, USA)

Chapter 6. Animal 'Pain' Models and Behavioral Tests in Preclinical Studies; pp. 223-239
(Backil Sung, Harvard Medical School, USA)

Chapter 7. Pain Assessment Tools used in Clinical Pain Management: Implications for Translational Research;
pp. 241-250
(Miroslav Backonja, Clinical Science Center, USA)

Chapter 8. Experimental Pain Testing: Measurement and Clinical Relevance;
pp. 251-267
(Robert R. Edwards, Johns Hopkins University School of Medicine, USA and Barbara Hastie, University of Florida College of Dentistry, USA)

Chapter 9. In Silico Genetic Analysis of Pain and Analgesia Related Traits;
pp. 269-292
(Guochun LiaoRoche Palo Alto, USA and David J. Clark, Stanford University, USA)

Chapter 10. Sex Differences in Pain: Translational Challenges and Opportunities;
pp. 293-314
(Roger B. Fillingim, University of Florida College of Dentistry, USA)

Chapter 11. Placebo Effects and Meaning Response: Perspectives from Consciousness Studies;
pp. 315-334
(Yoshio Nakamura, University of Utah School of Medicine, USA)

Chapter 12. Preclinical Studies of Intrathecal Analgesics;
pp. 335-382
(Cata and Patrick M. Dougherty, University of Texas, USA)

Chapter 13. Intrathecal Drug Delivery for Chronic Pain Management; pp. 383-402
(Shihab Ahmed)

Chapter 14. Spinal Cord Stimulation: Mechanisms and Clinical Application;
pp. 403-413
(Milan Stojanovic, Harvard Medical School, USA)

Chapter 15. Drug Delivery Methods;
pp. 415-451
(Steven P. Cohen and David Maine, Johns Hopkins School of Medicine, USA)


      Translational Pain Research - Jianren Mao (Mass. General Hospital, Harvard Medical School) - Series Editor
   Binding: Hardcover
   Pub. Date: 2006
   ISBN: 1-60021-206-9
   Status: AV
Status Code Description
AN Announcing
FM Formatting
PP Page Proofs
FP Final Production
EP Editorial Production
PR At Prepress
AP At Press
AV Available
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Translational Pain Research. Volume 1: Current Status and New Trends