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01.Gene Silencing: New Research
02.New Research on DNA Damage
03.Life Span Development in Genetic Disorders: Behavioral and Neurobiological Aspects
04.Myelin Basic Protein
05.New Research on Genomic Instability
06.Developmental Gene Expression Regulation
07.Lecture Notes on Computational Mutation
08.Fragile Sites: New Discoveries and Changing Perspectives
09.Progress in Stem Cell Applications
10.Genetic Vectors Research Focus
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The Cystatin Superfamily of Proteinase Inhibitors
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Authors: Philippe Taupin (National Neuroscience Institute, Singapore) 
Book Description:
This book aims at presenting an overview of the current knowledge of cystatins and molecles of the cystatin superfamily, their structure, physio-and pathological function as well as the direction that research is currently aiming for in developing therapeutic treatments based on cysteine proteinases and related molecules.
Its purpose is to give the reader a tool that serves as a reference in the field of protease inhibitor, their physio-and pathological functions and therapeutic potential. It also aims at making accessible to a broader audience, that does not have easy access to scientific publications, a source of knowledge and information.
To acheive this goal, the book aims at covering broadly, systematically, concisely, and in depth, the multifacets of the role of cystatins and molecules of the cystatin superfamily in physiopathology, and emphasize on their therapeutic potentials. Figures, self-explantory schemas and diagrams contribute to clarifying and support the data presented.

Table of Contents:

Chapter I - Stefins, Cystatins and Kininogens; pp. 5-13

Chapter II - The Cystatin Superfamily; pp. 15-21

Chapter III - Structure: Chicken Cystatin and Human Cystatin C;
pp. 23-28

Chapter IV - Cysteine Proteinase Inhibitors; pp. 29-39

Chapter V - Dimerization and Domain Swapping; pp. 41-47

Chapter VI - Amyloidosis and Amyloidogenic Proteins; pp. 49-56

Chapter VII - Physiology; pp. 57-67

Chapter VIII - Pathology & Therapy; pp. 69-78

Conclusion and Perspectives



   Binding: Hardcover
   Pub. Date: 2008, 1st quarter - C
   ISBN: 978-1-60456-010-7
   Status: AV
Status Code Description
AN Announcing
FM Formatting
PP Page Proofs
FP Final Production
EP Editorial Production
PR At Prepress
AP At Press
AV Available
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The Cystatin Superfamily of Proteinase Inhibitors